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Effects of m-nisoldipine and nisoldipine on electric activity of human atrial tissue

  
@article{APS6049,
	author = {Xiao-Ping Yang and Rui-Hai An and Rui-Rong He and Ying-Kui Xie and Shao-Xian Liu and Su Liu},
	title = {Effects of m-nisoldipine and nisoldipine on electric activity of human atrial tissue},
	journal = {Acta Pharmacologica Sinica},
	volume = {13},
	number = {2},
	year = {2016},
	keywords = {},
	abstract = {Using intracellular microelectrode technique and microcomputer analyzing system, the effects of m-nisoldipine (m-Nis) and nisoldipine (Nis) on spontaneous electric activity of human atrial tissue were studied. APA and Vmax were remarkably decreased by m-Nis (0.25 and 1.25 mumol.L-1) and Nis (0.25 mumol.L-1). RPF was also greatly decreased as a result of inhibition in VDD. The inhibitory effects of m-Nis on transmembrane potentials were less than those of Nis at equal concentration (0.25 mumol.L-1). Neither MDP nor APD90 was affected by m-Nis and Nis.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/6049}
}