TY - JOUR AU - Chen Huai Gu AU - Sawyer Tomi K AU - Wuts Peter G M PY - 2016 TI - Synthesis of a new hydroxyethylene dipeptide isostere Phe psi [CH2CH (OH)]Phe as HIV-1 protease inhibitor JF - Acta Pharmacologica Sinica; Vol 15, No 1 (January 1994): Acta Pharmacologica Sinica Y2 - 2016 KW - N2 - A new type of pseudopeptide isostere exampled by Phe psi[CH2CH(OH)]Phe was synthesized from phenylalanine. The HIV protease inhibitory activity (IC50) of Noa-His-Phe psi[CH2CH(OH)]Phe-Ile-Amp was 0.8 pmol.L-1. UR - http://www.chinaphar.com/article/view/6021