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Effects of cysteamine on flexion reflex facilitation by C-primary afferents in cats

  
@article{APS5788,
	author = {Chong-qing Li and Zhi-qi Zhao and Huan-qiao Yang},
	title = {Effects of cysteamine on flexion reflex facilitation by C-primary afferents in cats},
	journal = {Acta Pharmacologica Sinica},
	volume = {12},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {Brief (20 s) conditioning stimuli at C-fiber intensity applied to the sural or gastrocnemius nerve evoked a facilitation of the flexor alpha-motoneurone discharges from small filaments of the posterior biceps semitendinosus nerve produced by subcutaneous stimulation of the plantar region in anesthetized spinal cats. Such C afferent-induced facilitation was blocked reversibly by cysteamine (50 mg.kg-1), a somatostatin depletor, without affecting the basic mechanisms of flexor reflexes, suggesting an important role played by somatostatin in transmission and/or modulation of nociceptive information in the spinal cord.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/5788}
}