@article{APS5779,
author = {Chun-wen SHAN and Su-qin YANG and Han-dan HE and Su-lan SHAO and Pei-wen ZHANG},
title = {Influences of 3,4,5-trihydroxystibene-3-beta-mono-D-glucoside on rabbits' platelet aggregation and thromboxane B2 production in vitro},
journal = {Acta Pharmacologica Sinica},
volume = {11},
number = {6},
year = {2016},
keywords = {},
abstract = {Platelet aggregation and thromboxane B2 (TXB2) production induced by arachidonic acid (AA) or Adenosine diphosphate (ADP) were studied by turbidimetry and radioimmunoassay in rabbits. 3,4,5-tri-hydroxystibene-3-beta-mono-D-glucoside (PD) 6.7-107.2 mumol/L inhibited platelet aggregation and the production of TXB2 as well. The inhibitions by PD were dose-dependent: 48-90% (AA-induced) and 43-69% (ADP-induced) for platelet aggregation; 50-87% (AA-induced) and 43-68% (ADP-induced) for TXB2. There were positive correlations between the inhibition of platelet aggregation and production of TXB2.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/5779}
}