@article{APS5726,
author = {Guo-wei Sang and Xin-hua Liu and Qing-xiang Shao and Jun-li Ge and Shu-mei Mao and Feng-ying Lu},
title = {Pharmacokinetics of norethindrone enanthate 200 mg after intramuscular injection in 25 Chinese women},
journal = {Acta Pharmacologica Sinica},
volume = {12},
number = {2},
year = {2016},
keywords = {},
abstract = {Pharmacokinetic profile was studied in 25 healthy fertile Chinese female volunteers after im norethindrone enanthate (NET-EN) 200 mg. The results were compared with the data from British women in our previous paper. Following a single im NET-EN 200 mg, the times to reach peak levels of NET-EN and NET were 4.0 +/- 2.8 d and 5.4 +/- 2.0 d, and their peak values were 5.0 +/- 1.8 and 12.6 +/- 0.9 ng.ml-1, respectively. Mean elimination T1/2 of NET was significantly longer than that of NET-EN. Mean apparent elimination T1/2 were 14.8 +/- 3.8 d for and 11.4 +/- 5.7 d for NET-EN. The elimination rate of NET in Chinese women was significantly slower than that in British women. There was no significant ethnic difference in absorption kinetics of NET and NET-EN.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/5726}
}