@article{APS5521,
author = {Lin Liu and Min Zhang and Ping Zou},
title = {Expression of PLK1 and survivin in non-Hodgkin's lymphoma treated with CHOP},
journal = {Acta Pharmacologica Sinica},
volume = {29},
number = {3},
year = {2016},
keywords = {},
abstract = {Aim: The present study was designed to investigate the expression of Polo-like kinase 1 (PLK1) and survivin in non-Hodgkin's lymphoma (NHL).
Methods: The expression of PLK1 and survivin were detected with immunohistochemical techniques.
Results: The expression rate of PLK1 and survivin were 63.6% (56/88) and 79.5% (70/88) in NHL, respectively. PLK1 expression correlated with systemic symptoms, lactate dehydrogenase levels, and international prognostic index scores in B-NHL and T-NHL, while survivin did not.
Conclusion: PLK1 and survivin are both overexpressed in NHL. There is a significant relationship between the overexpression of PLK1 and clinical features.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/5521}
}