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Biological N-oxidation of piperidine in vitro

   
@article{APS5445,
	author = {Dian-ying Wang and John W Gorrod and Arnold H Beckett},
	title = {Biological N-oxidation of piperidine in vitro},
	journal = {Acta Pharmacologica Sinica},
	volume = {10},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {The biological N-oxidation of piperidine, a pharmacologically active biogenic amine of mammals and human beings, was studied in vitro. After incubation of piperidine-HCl in a fortified rat liver microsomal preparation (9000 x g supernatant) at 37 degrees C for 30 min, 2 metabolites were detected. They were identified as N-hydroxy piperidine and 2, 3, 4, 5-tetrahydro-pyridine-1-oxide as evidenced by TLC, GLC, HPLC, GC-MS and MS.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/5445}
}