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Hemodynamic effects of zinc sulfate on anesthetized open-chest dogs

  
@article{APS5440,
	author = {Feng-jun Ma and Geng-sheng Zhao and Xiao-guang Li},
	title = {Hemodynamic effects of zinc sulfate on anesthetized open-chest dogs},
	journal = {Acta Pharmacologica Sinica},
	volume = {10},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {ZnSO4 3-5 mg/kg iv decreased systolic blood pressure, diastolic blood pressure and mean arterial blood pressure, +dP/dtmax, -dP/dtmax, VCE- +dP/dtmax, and left ventricular systolic pressure. However, ZnSO4 had no significant effects on T values and total peripheral resistance. In addition, ZnSO4 obviously decreased heart rate and cardiac index. These results suggest that iv ZnSO4 may cause hypotension via cardiac inhibition.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/5440}
}