@article{APS5432,
author = {Ping-jun Zhu and Yao-chun Liu and Zhen-yuan Li and De-zhang Yu},
title = {Electrophysiologic effects of sophocarpine on papillary muscle in guinea pig},
journal = {Acta Pharmacologica Sinica},
volume = {10},
number = {3},
year = {2016},
keywords = {},
abstract = {Sophocarpine prolonged the action potential duration of guinea pig papillary muscle in a dose-dependent manner. After the preparations were exposed to sophocarpine 50 mumol/L for 30 min, APD50 and APD90 were prolonged from 189 +/- 21 and 216 +/- 24 ms to 205 +/- 27 and 241 +/- 25 ms (P less than 0.01). Simultaneously, ERP was prolonged from 202 +/- 14 to 211 +/- 16 ms, although the ERP/APD90 ratio was not changed. Sophocarpine had no significant effects on other AP parameters. Propranolol did not block sophocarpine effects.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/5432}
}