How to cite item

Characterization of histamine receptors in tracheal smooth muscle of Mastomys natalensis

   
@article{APS5297,
	author = {Rakesh Shukla and Rikhab Chand Srimal and Bhola Nath Dhawan},
	title = {Characterization of histamine receptors in tracheal smooth muscle of Mastomys natalensis},
	journal = {Acta Pharmacologica Sinica},
	volume = {10},
	number = {1},
	year = {2016},
	keywords = {},
	abstract = {The tracheal smooth muscle of Mastomys natalensis contracted with carbachol administration while histamine (H) caused concentration-dependent relaxation. The Specific H2-receptor agonists 4-methyl histamine, dimaprit, impromidine and a high concentration of 2-methyl histamine (H1-agonist) caused relaxation similar to H which was selectively blocked by cimetidine. Low concentrations (10(-5)-10(-4) mol/L) of 2-methyl histamine and of H (10(-8)-10(-7) mol/L) occasionally produced small contractions. Mepyramine (pyrilamine) blocked the contraction but did not modify the relaxant effect of H and its agonists. The results suggest a preponderance of histamine H2-inhibitory receptors in the trachea of this animal.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/5297}
}