@article{APS5287,
author = {Bo-jun YUAN and Bao-chun LI and Nian-ci SHEN},
title = {Evaluation of phototoxic effects of chlorquine and eleven other antimalarials in mice},
journal = {Acta Pharmacologica Sinica},
volume = {7},
number = {5},
year = {2016},
keywords = {},
abstract = {The phototoxicity of anti-malarials was studied in mice that were irradiated for 24 h with black light in 22+/-1 degrees. No phototoxicity was observed within 7 d in mice after: 1) ig 1/4 LD50 with 12 antimalarials (chloroquine phosphate, piperaquine phosphate, hydroxypiperaquine phosphate, quinine sulfate, mefloquine hydrochloride, cycloquine hydrochloride, mequinacrine hydrochloride, artesunate (sodium dihydroartemisinin succinate), pyronaridine phosphate, cyclochloroquanide hydrochloride, pyrimethamine, primaquine phosphate); 2) iv 1/2-1/4 LD50 with the former 4 drugs; 3) ip 1/8 LD50 qd*7 d with the former 5 drugs.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/5287}
}