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Effects of tetrandrine on positive staircase phenomena and post-rest potentiation of contraction of isolated guinea pig left atrium

   
@article{APS5249,
	author = {Gang Wang and Bin Cheng and Xian-Gang Zong and Da-Chao Fang and Ming-Xing Jiang},
	title = {Effects of tetrandrine on positive staircase phenomena and post-rest potentiation of contraction of isolated guinea pig left atrium},
	journal = {Acta Pharmacologica Sinica},
	volume = {8},
	number = {6},
	year = {2016},
	keywords = {},
	abstract = {Tetrandrine (Tet) 0.32 mmol/ L and verapamil (Ver) 30 μmol/L inversed positive staircase phenomena of contraction in left atrium of guinea pig. After the preparation was partially depolarized with K+ 20 mmol/L, such effect of Tet and Ver became much greater. Propranolol could not inverse the positive staircase phenomena. In addition, after the treatment of Tet 0.32 mmol/L for 20 min the post-rest potentiation of myocardial contraction in the left atrium was depressed by 2.8±0.3g (p},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/5249}
}