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Genetic effects of fluorocarbon emulsion on germinal cells of male mice

   
@article{APS5038,
	author = {Bao-zhen ZHONG and Qi-ni TANG and Pei-jun XIN and Bing-sheng WANG},
	title = {Genetic effects of fluorocarbon emulsion on germinal cells of male mice},
	journal = {Acta Pharmacologica Sinica},
	volume = {7},
	number = {4},
	year = {2016},
	keywords = {},
	abstract = {The A strain male mice were infused with fluorocarbon emulsion (FCE) 50, 10 ml/kg and NS 50 ml/kg. Metaphase plates of spermatogonia and spermatocytes I were examined on d 7 after infusion and histological damage of the testes was studied by light and electron microscopes.
The frequencies of aneuploid and polyploidy of spermatogonia were 2.9, 2.5, and 1.4%, respectively induced by FCE 50, 10 ml/kg and NS 50 ml/kg. While those of breaks and reciprocal translocations were 0.5, 0.1 and 0.2%, respectively. In spermatocytes I the frequency of X-Y univalent and autosomal univalent were 2% (P},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/5038}
}