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Effect of oxymatrine on isolated heart atria of rabbits

	author = {Rui-song LI and Xiu-juan YAO and Shui-ying CHEN and Yu-ping RUAN},
	title = {Effect of oxymatrine on isolated heart atria of rabbits},
	journal = {Acta Pharmacologica Sinica},
	volume = {7},
	number = {3},
	year = {2016},
	keywords = {},
	abstract = {Oxymatrine, isolated from Sophora alopecuroides, increased the contractility of the left heart atrium of rabbit dose-dependently and decreased the contractility and excitability, when the cumulative dose reached the toxic level (360 microM).
Oxymatrine 9 microM increased the automaticity induced by epinephrine and shortened the functional refractory period, but did not shift the intensity-duration curve. On the right atrium oxymatrine 9 microM also decreased the spontaneous rate and the positive chronotropic effect induced by CaCl2.},
	issn = {1745-7254},	url = {}