@article{APS4978,
author = {Rui-song LI and Xiu-juan YAO and Shui-ying CHEN and Yu-ping RUAN},
title = {Effect of oxymatrine on isolated heart atria of rabbits},
journal = {Acta Pharmacologica Sinica},
volume = {7},
number = {3},
year = {2016},
keywords = {},
abstract = {Oxymatrine, isolated from Sophora alopecuroides, increased the contractility of the left heart atrium of rabbit dose-dependently and decreased the contractility and excitability, when the cumulative dose reached the toxic level (360 microM).
Oxymatrine 9 microM increased the automaticity induced by epinephrine and shortened the functional refractory period, but did not shift the intensity-duration curve. On the right atrium oxymatrine 9 microM also decreased the spontaneous rate and the positive chronotropic effect induced by CaCl2.},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/4978}
}