TY - JOUR AU - TAO Zheng-qin AU - CHEN Zhen-jia AU - ZHANG Jian-shi AU - DING Guang-sheng PY - 2016 TI - Affinity of 99mTc-N,N-bis-(carboxymethyl) aminoacetylproline for tumors in mice JF - Acta Pharmacologica Sinica; Vol 7, No 2 (March 1986): Acta Pharmacologica Sinica Y2 - 2016 KW - N2 - In mice the radioactivities of 99mTc-N, N-bis-(carboxymethyl) amino-acetylproline after iv 0.37 MBq/0.5 mg/mouse showed a high affinity for 4 transplanted tumors of mice-higher in uterocervical carcinoma-14 and hepatoma than in sarcoma 180 and Lewis lung carcinoma. The radioactivities in blood, femur, brain, heart, lungs, muscles and spleen were lower, whereas those in kidneys and liver were higher, than that in the tumors. The tumor/organ ratios maintained a high level during the period of 3-12 h after iv. UR - http://www.chinaphar.com/article/view/4913