TY - JOUR AU - SHI Jue-min AU - CHEN Xue-xin AU - ZHANG Wen-juan AU - ZHOU Ming-hua AU - YANG Jia-luo AU - YIN Yao-cheng PY - 2016 TI - Toxicity of medium chain triglycerides and its influence on serum cholesterol JF - Acta Pharmacologica Sinica; Vol 7, No 2 (March 1986): Acta Pharmacologica Sinica Y2 - 2016 KW - N2 - Medium chain triglycerides (MCT), a kind of neutral fats extracted from camphor tree drupes and composed mainly of C10 saturated fatty acid triglycerides, were hydrolyzed and absorbed rapidly. When dogs were fed MCT 2 or 5 ml/kg/d for 102 d there were no remarkable changes in ECG, hematological and histological examinations, as well as hepatic and renal function tests. The blood content of MCFA reached the peak at 1.5 h after feeding and then declined in 4 h. MCT reduced serum and liver cholesterol levels in rabbits, rats, and dogs. MCT is very stable and can safely be used as medicine and nutriment. UR - http://www.chinaphar.com/article/view/4905