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Comparison of the mutagenicity of 4 nitrofurans in a Salmonella/microsome system

   
@article{APS4780,
	author = {Yi-chang Ni and Yue-qin Xu and Bao-ruo Shao},
	title = {Comparison of the mutagenicity of 4 nitrofurans in a Salmonella/microsome system},
	journal = {Acta Pharmacologica Sinica},
	volume = {6},
	number = {2},
	year = {2016},
	keywords = {},
	abstract = {Mutagenicity of 4 nitrofurans were determined at various concentrations in 4 histidine-requiring strains of Salmonella typhimurium, with or without liver microsomal metabolic activation. The concentration-effect curves of mutagenicity of 4 nitrofurans were also tested in the sensitive strain, TA 100. The proper order of mutagenicity of 4 nitrofurans tested is furazolidone>M-254>furapyrimidone>nitrofurantoin, by comparisons of both the positive dose ranges in TA 100 and TA 98 and the concentration-effect curves in TA 100.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/4780}
}