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Antifertility effects of 2 alpha, 17 alpha-diethynyl, A-nor-androstane, 2 beta,17 beta-dihydroxy, 2 beta-semisuccinate (AF-57)

  
@article{APS4770,
	author = {Zhi-ping Gu and Wei-cheng Wang and Li-men Qi and Pei-juan Shen and Shi-xing Zhao and Rui-lin Li},
	title = {Antifertility effects of 2 alpha, 17 alpha-diethynyl, A-nor-androstane, 2 beta,17 beta-dihydroxy, 2 beta-semisuccinate (AF-57)},
	journal = {Acta Pharmacologica Sinica},
	volume = {6},
	number = {2},
	year = {2016},
	keywords = {},
	abstract = {AF-57,a analogue ofanordrin, demonstrated antifertility effects in rats, mice, hamsters and rabbits,depressed the fuction of corpora lutea in rabbits and caused a retardation of cleavage and degeneration of ova in hamsters. The estrogenicity of AF-57 was lower than that of anordrin in mice, but similar to anordrin in rats. AF-57 showed a higher binding ability than anordrin to cytosol estrogenic receptors of uteri in rats.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/4770}
}