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Anti-slow reacting substance of anaphylaxis effect of verapamil

   
@article{APS4752,
	author = {Hong-quan Zhang and Ru-lian Bian},
	title = {Anti-slow reacting substance of anaphylaxis effect of verapamil},
	journal = {Acta Pharmacologica Sinica},
	volume = {6},
	number = {2},
	year = {2016},
	keywords = {},
	abstract = {Verapamil significantly inhibited the contraction of guinea pig tracheal and lung strips induced by SRS-A 100 U/mL in vitro. Verapamil also inhibited the contraction of human bronchial and lung strips induced by SRS-A 100 U/Ml in vitro. Pretreatment of verapamil 25 mg/kg iv antagonized the augmentation of respiratory airflow induced by SRS-A. Verapamil alleviated the asthmatic attacks of guinea pig induced by SRS-A. The anti- SRS-A effect of verapamil was reduced, when the extracellular Ca2+ level was elevated, and vice versa.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/4752}
}