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Hypotensive effect of nevadensin

	author = {Jie-yun Song and Xiu-ze He and Xiu-fen Chen and Ju-ying Hu and Gui-ying Luo and Yan-zhu Mo},
	title = {Hypotensive effect of nevadensin},
	journal = {Acta Pharmacologica Sinica},
	volume = {6},
	number = {2},
	year = {2016},
	keywords = {},
	abstract = {In anesthetized dogs and cats, iv,im or intraduodenal injection of nevadensin 2-40 mg/kg lowered the BP 64±7 mmHg, but the heart rate and respiration remained unchanged. The BP gradually returned to its original level in 2-4 h. In dogs the BP was lowered more by nevadensin (2 mg/kg) than by reserpine(1.5 mg/kg) or hexamethonium.The hypotensive effect of nevadensin and total alkaloids of Rauwolfia were similar. The mechanism of its hypotensive action appears to be both central and peripheral in nature.},
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