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Effect of l-tetrahydropalmatine on sleep-waking cycle of cats

   
@article{APS4618,
	author = {C BUDA and M SALLANON and Guo-Zhang JIN},
	title = {Effect of l-tetrahydropalmatine on sleep-waking cycle of cats},
	journal = {Acta Pharmacologica Sinica},
	volume = {5},
	number = {1},
	year = {2016},
	keywords = {},
	abstract = {After ip  l-THP 30 to 80 mg/kg in cats, SWS-2, PS and PGO discharges were eliminated. At 80 mg/kg, l-THP interrupted the sleep waking cycle by inducing a notable state of excitation, which lasted 12-30 h. At 30 or 40 mg/kg, the effect of l-THP lasted 10 h; waking was decreased and SWS-1 increased with sedation, but the arousal response was maintained. This effect at 30 or 40 mg/kg is similar to that shown by other tranquillizing drugs or DA-receptor antagonists.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/4618}
}