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Action of 15-methyl-prostaglandin F2 alpha on progesterone receptors and estradiol receptors in rabbit uterus

   
@article{APS4616,
	author = {Yun-hong Chu and Mei-hua Zhou and Quan Li and Zi-fang Zhao},
	title = {Action of 15-methyl-prostaglandin F2 alpha on progesterone receptors and estradiol receptors in rabbit uterus},
	journal = {Acta Pharmacologica Sinica},
	volume = {3},
	number = {4},
	year = {2016},
	keywords = {},
	abstract = {15-Methyl-PGFiv to pseudopregnant and immature rabbits increased the amount of progesterone receptors (P-R) in uteri. The increase of P-R in pseudopregnant uteri was more marked than that in immature uteri. But no striking change of estradiol receptors and of Ka of both receptors was observed. Injection of 15-methyl-PGFto pseudopregnant rabbits decreased the plasma progesterone level, but did not enhance the spontaneous contraction of uteri.
  It is suggested that 1) The mechanism of the increase of P-R in uterus is mediated mainly through the luteolytic action of 15-methyl-PGF; 2) The P-R in uterus plays a role in regluation of uterine contraction.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/4616}
}