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A quantitative structure-activity study on artemisinine analogues

  
@article{APS4499,
	author = {Ji-an Wu and Ru-yun Ji},
	title = {A quantitative structure-activity study on artemisinine analogues},
	journal = {Acta Pharmacologica Sinica},
	volume = {3},
	number = {1},
	year = {2016},
	keywords = {},
	abstract = {Artemisinine is a natural constituent with antimalarial activity. Various ethers and esters were synthesized in our Institute. Their antimalarial activities were expressed in terms of SD90. Attempts were made to study the QSAR through Hansch analysis.
  We determined the log P values of various compounds from 1-octanol/water system by HPLC. For compounds of higher log P values (3.0—5.0), 60% methanol was employed for elution, and for those of lower log P values (},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/4499}
}