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Distribution and excretion of [35S]NaHSO3-andrographolide by autoradiography

	author = {Shou-peng Zhu and Bao-an Kang},
	title = {Distribution and excretion of [35S]NaHSO3-andrographolide by autoradiography},
	journal = {Acta Pharmacologica Sinica},
	volume = {2},
	number = {4},
	year = {2016},
	keywords = {},
	abstract = {The autoradiographic study indicated that 2 h after iv [35S]NaHSO3-andrographolide (AG) in rats the radioactivity accumulated chiefly in the duodenum. In the CNS the radioactivity accumulated mainly in the cephalic end of spinal cord with a distribution of descending type. AG was excreted rapidly. The biological t1/2=2 h.
The urine was tested by paper radiochromatographic scan and liquid scintillation counter. A single peak corresponding to the R(F) o authentic AG was found. AG was excreted chiefly in the urine and probably in the unchanged form.},
	issn = {1745-7254},	url = {}