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The schistosomicidal effect of bromo-acetoacetic ester compounds

   
@article{APS4110,
	author = {Han-ying Yan and Ye-hao Yang and Shi-li Gui and Yan-qin Zhu and Zhong-qiang Yin and Li-zhuo Wang and Gu-sheng Zhang and Xie-ming Qian},
	title = {The schistosomicidal effect of bromo-acetoacetic ester compounds},
	journal = {Acta Pharmacologica Sinica},
	volume = {2},
	number = {1},
	year = {2016},
	keywords = {},
	abstract = {Mice were injected with Schistosoma japonicum. Seventy bromo-acetoacetic esters were screened. They included aliphatic, aromatic and heterocyclic alcoholic and phenolic esters of bromoacetic acid. Among them, hydroxyl-cumarin derivatives of bromo-acetoacetic esters scored the highest % of hit, and all of the 15 compounds were effective. The other groups had different degrees of schistosomicidal effects. Their parasiticidal actions may be related to the bromo-acetoacetic group.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/4110}
}