@article{APS3767,
author = {Li-ping Zhang and Jing-xiang Yin and Zheng Liu and Yi Zhang and Qing-shan Wang and Juan Zhao},
title = {Effect of resveratrol on L-type calcium current in rat ventricular myocytes},
journal = {Acta Pharmacologica Sinica},
volume = {27},
number = {2},
year = {2016},
keywords = {},
abstract = {Aim: To study the effect of resveratrol on L-type calcium current (ICa-L) in isolated
rat ventricular myocytes and the mechanisms underlying these effects. Methods:
ICa-L was examined in isolated single rat ventricular myocytes by using the whole
cell patch-clamp recording technique. Results: Resveratrol (10–40 μmol/L) reduced
the peak amplitude of ICa-L and shifted the current-voltage (I–V) curve
upwards in a concentration-dependent manner. Resveratrol (10, 20, 40 μmol/L)
decreased the peak amplitude of ICa-L from -14.2±1.5 pA/pF to -10.5±1.5 pA/pF
(P},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/3767}
}