TY - JOUR AU - KONTERMANN Roland E PY - 2016 TI - Recombinant bispecific antibodies for cancer therapy JF - Acta Pharmacologica Sinica; Vol 26, No 1 (January 2005): Acta Pharmacologica Sinica Y2 - 2016 KW - N2 - Bispecific antibodies can serve as mediators to retarget effector mechanisms to disease-associated sites. Studies over the past two decades have revealed the potentials but also the limitations of conventional bispecific antibodies. The evelopment of recombinant antibody formats has opened up the possibility of generating bispecific molecules with improved properties. This review summarizes recent developments in the field of recombinant bispecific antibodies and discusses further requirements for clinical development. UR - http://www.chinaphar.com/article/view/3518