How to cite item

Pyroptosis and pyroptosis-inducing cancer drugs

   
@article{APS10676,
	author = {Fan Yang and Sahana N. Bettadapura and Mark S. Smeltzer and Hua Zhu and Shanzhi Wang},
	title = {Pyroptosis and pyroptosis-inducing cancer drugs},
	journal = {Acta Pharmacologica Sinica},
	volume = {43},
	number = {10},
	year = {2022},
	keywords = {},
	abstract = {Pyroptosis, an inflammatory form of lytic cell death, is a type of cell death mediated by the gasdermin (GSDM) protein family. Upon recognizing exogenous or endogenous signals, cells undergo inflammasome assembly, GSDM cleavage, the release of proinflammatory cytokines and other cellular contents, eventually leading to inflammatory cell death. In this review, we discuss the roles of the GSDM family for anti-cancer functions and various antitumor drugs that could activate the pyroptosis pathways.},
	issn = {1745-7254},	url = {http://www.chinaphar.com/article/view/10676}
}