@article{APS10398,
author = {Rui Li and Hong Wang and Fei Ma and Guang-lin Cui and Li-yuan Peng and Chen-ze Li and He-song Zeng and Ali J. Marian and Dao-wen Wang},
title = {Widespread myocardial dysfunction in COVID-19 patients detected by myocardial strain imaging using 2-D speckle-tracking echocardiography},
journal = {Acta Pharmacologica Sinica},
volume = {42},
number = {10},
year = {2021},
keywords = {},
abstract = {COVID-19 is a multiorgan systemic inflammatory disease caused by SARS-CoV-2 virus. Patients with COVID-19 often exhibit cardiac dysfunction and myocardial injury, but imaging evidence is lacking. In the study we detected and evaluated the severity of myocardial dysfunction in COVID-19 patient population using two-dimensional speckle-tracking echocardiography (2-D STE). A total of 218 consecutive patients with confirmed diagnosis of COVID-19 who had no underlying cardiovascular diseases were enrolled and underwent transthoracic echocardiography. This study cohort included 52 (23.8%) critically ill and 166 noncritically ill patients. Global longitudinal strains (GLSs) and layer-specific longitudinal strains (LSLSs) were obtained using 2-D STE. Changes in GLS were correlated with the clinical parameters. We showed that GLS was reduced (},
issn = {1745-7254}, url = {http://www.chinaphar.com/article/view/10398}
}