Editorial

A new era for GPCR research: structures, biology and drug discovery [P 289-290]
H Eric XU, Rui-ping XIAO
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Review

Structure and activation of rhodopsin [P 291-299]
X Edward ZHOU, Karsten MELCHER, H Eric XU
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Structure and mechanism for recognition of peptide hormones by Class B G-protein-coupled receptors [P 300-311]
Kuntal PAL, Karsten MELCHER, H Eric XU
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Structure and ligand recognition of class C GPCRs [P 312-323]
Lei CHUN, Wen-hua ZHANG, Jian-feng LIU
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Ice breaking in GPCR structural biology [P 324-334]
Qiang ZHAO, Bei-li WU
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β-Adrenergic receptor subtype signaling in heart: From bench to bedside [P 335-341]
Anthony Yiu Ho WOO, Rui-ping XIAO
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Role of G protein-coupled receptors in inflammation [P 342-350]
Lei SUN, Richard D YE
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GPCRs and cancer [P 351-362]
Rosamaria LAPPANO, Marcello MAGGIOLINI
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Orphan G protein-coupled receptors (GPCRs): biological functions and potential drug targets  [P 363-371]
Xiao-long TANG, Ying WANG, Da-li LI, Jian LUO, Ming-yao LIU
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Tools for GPCR drug discovery [P 372-384]
Ru ZHANG, Xin XIE
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Original Article

Neuropharmacology

Rapamycin prevents the mutant huntingtin-suppressed GLT-1 expression in cultured astrocytes [P 385-392]
Lei-lei CHEN, Jun-chao WU, Lin-hui WANG, Jin WANG, Zheng-hong QIN, Marian DIFIGLIA, Fang LIN
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Cardiovascular Pharmacology

High-sodium intake aggravates myocardial injuries induced by aldosterone via oxidative stress in Sprague-Dawley rats [P 393-400]
Jing-yi LI, Shao-ling ZHANG, Meng REN, Yan-ling WEN, Li YAN, Hua CHENG
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Anti-tumor Pharmacology

Heterogeneity of chemosensitivity in esophageal cancer using ATP-tumor chemo­sensitivity assay [P 401-406]
Zhi-qiang LING, Chun-jian QI, Xiao-xiao LU, Li-juan QIAN, Lin-hui GU, Zhi-guo ZHENG, Qiang ZHAO, Shi WANG, Xian-hua FANG, Zhi-xing YANG, Jian YIN, Wei-min MAO
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Novel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G₂-M arrest and apoptosis in HeLa cells [P 407-417]
Yi-ming MA, Yu-bo ZHOU, Chuan-ming XIE, Dong-mei CHEN, Jia LI
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Drug Discovery

Thiazolidione derivatives targeting the histidine kinase YycG are effective against both planktonic and biofilm-associated Staphylococcus epidermidis [P 418-425]
Ren-zheng HUANG, Li-kang ZHENG, Hua-yong LIU, Bin PAN, Jian HU, Tao ZHU, Wei WANG, Dan-bin JIANG, Yang WU, You-cong WU, Shi-qing HAN, Di QU 
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Letter

Differential sensitivity of RIP3-proficient and deficient murine fibroblasts to camptothecin anticancer drugs  [P 426-428]
Jin-xue HE, Ying-qing WANG, Jian-ming FENG, Jia-xin LI, Lei XU, Xiao-hua LI, Wei WANG, Xia-juan HUAN, Yi JIANG, Bing YU, Guang CHEN, Ze-hong MIAO
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