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Editorial

Acta Pharmacologica Sinica: Celebrating 30 years of publishing [P 1013-1014]
Jian DING
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Perspective

Double target concept for smoking cessation [P 1015-1018]
Jie WU

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Emerging role of junctophilin-2 as a regulator of calcium handling in the heart [P 1019-1021]
Alejandro GARBINO, Xander HT WEHRENS

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New perspectives on vascular wall signaling: role of perivascular adipocytes and fibroblasts [P 1022-1025]
Chiu-Yin KWAN, Wen-Tsong Hsieh, Peter Nim-Hin To, Hui-Di WANG

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Non-peptidic glucagon-like peptide-1 receptor agonists: aftermath of a serendipitous discovery [P 1026-1030]
Ming-wei WANG, Qing LIU, Cai-hong ZHOU

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Kv1.3: a potential pharmacological target for diabetes [P 1031-1035]
Bok Hee CHOI, Sang June HAHN

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Review

Hyperpolarization-activated, cyclic nucleotide-gated (HCN) channels in the regulation of midbrain dopamine systems [P 1036-1043]
Hong-yuan CHU, Xuechu ZHEN
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Recent advances in (patho)physiology of astroglia [P 1044-1054]
Alexei VERKHRATSKY, Vladimir PARPURA
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Genetics of stroke [P 1055-1064]
Jin-min GUO, Ai-jun LIU, Ding-feng SU
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The role of κ-opioid receptor activation in mediating antinociception and addiction [P 1065-1064]
Yu-hua WANG, Jian-feng SUN, Yi-min TAO, Zhi-qiang CHI, Jing-gen LIU
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Inhibitory role of oxytocin in psychostimulant-induced psychological dependence and its effects on dopaminergic and glutaminergic transmission [P 1071-1074]
Jing-yu YANG, Jia QI, Wen-yan HAN, Fang WANG, Chun-fu WU
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AMPK in cardiovascular health and disease  [P 1075-1084]
Najeeb A SHIRWANY, Ming-Hui ZOU
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Hypoxia inducible factor 1 (HIF-1) and cardioprotection [P 1085-1094]
Demet TEKIN, Ali D DURSUN, Lei XI 
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COX-mediated endothelium-dependent contractions: from the past to recent discoveries [P 1095-1102]
Michael Sze-Ka WONG, Paul Michel VANHOUTTE  
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Therapeutic implications of chemokine-mediated pathways in atherosclerosis: realistic perspectives and utopias [P 1103-1110]
Stavros APOSTOLAKIS, Virginia AMANATIDOU, Demetrios A SPANDIDOS
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Caloric restriction and heart function: is there a sensible link? [P 1111-1117]
Xuefeng HAN, Jun REN
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Cathelicidins in inflammation and tissue repair: Potential therapeutic applications for gastrointestinal disorders [P 1118-1122]
William Ka Kei WU, Clover Ching Man WONG, Zhi Jie LI, Lin ZHANG, Shun Xiang REN, Chi Hin CHO
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Type І natural killer T cells: naturally born for fighting [P 1123-1132]
Jin-quan TAN, Wei XIAO, Lan WANG, Yu-ling HE
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Clinical application and evaluation of anti-TNF-alpha agents for the treatment of rheumatoid arthritis [P 1133-1140]
Juan JIN, Yan CHANG, Wei WEI 
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Fragile privileges: autoimmunity in brain and eye [P 1141-1148]
Hartmut WEKERLE, De-ming SUN  
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Purinergic signaling: a novel mechanism in immune surveillance [P 1149-1153]
Lin MEI, Wei DU, Wei GAO, Qi-bing MEI
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Autophagic pathways as new targets for cancer drug development [P 1154-1164]
Bo Liu, Yan CHENG, Qian LIU, Jin-ku BAO, Jin-Ming YANG
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Chromosome 1q21 amplification and oncogenes in hepatocellular carcinoma [P 1165-1171]
Leilei CHEN, Tim Hon Man CHAN, Xin-yuan GUAN
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Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics [P 1172-1180]
Jin-xue HE, Chun-hao YANG, Ze-hong MIAO
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Potential therapeutics specific to c-MET/RON receptor tyrosine kinases for molecular targeting in cancer therapy [P 1181-1188]
Ming-Hai WANG, Snehal S PADHYE, Sunny GUIN, Qi MA, Yong-qing ZHOU
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ZSTK474, a novel phosphatidylinositol 3-kinase inhibitor identified using the JFCR39 drug discovery system [P 1189-1197]
De-xin KONG, Takao YAMORI
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Research and development of next generation of antibody-based therapeutics [P 1198-1207]
Jing LI, Zhenping ZHU
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The role of p53 in cell metabolism [P 1208-1212]
Xing-ding ZHANG, Zheng-hong QIN, Jin WANG
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Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors [P 1213-1222]
Dong-Soon IM
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Original Article

Regulation of Nrf2- and AP-1-mediated gene expression by epigallocatechin-3-gallate and sulforaphane in prostate of Nrf2-knockout C57BL/6J mice and PC-3 AP-1 human prostate cancer cells [P 1223-1240]
Sujit NAIR, Avantika BARVE, Tin-Oo KHOR, Guo-xiang SHEN, Wen LIN, Jefferson Y CHAN, Li CAI, Ah-Ng KONG
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