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Original Articles

Neuropharmacology

Ferulic acid inhibits nitric oxide-induced apoptosis by enhancing GABAB1 receptor expression in transient focal cerebral ischemia in rats [P 889-899]
Chin-yi CHENG, Shan-yu SU, Nou-ying TANG, Tin-yun HO, Wan-yu LO, Ching-liang HSIEH

[ Abstract ][ Full text ]

Morin exerts neuroprotective actions in Parkinson disease models in vitro and in vivo [P 900-906]
Zhen-tao ZHANG, Xue-bing CAO, Nian XIONG, Hong-cai WANG, Jin-sha HUANG, Sheng-gang SUN, Tao WANG

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Intracisternal or intrathecal glycine, taurine, or muscimol inhibit bicuculline-induced allodynia and thermal hyperalgesia in mice [P 907-914]
Il-ok LEE, Eui-sung LIM

[ Abstract ][ Full text ]

State-dependent blockade of human ether-a-go-go-related gene (hERG) K+ channels by changrolin in stably transfected HEK293 cells [P 915-922]
Wei-hai CHEN, Wen-yi WANG, Jie ZHANG, Ding YANG, Yi-ping WANG
[ Abstract ][ Full text ]

Magnesium lithospermate B extracted from Salvia miltiorrhiza elevats intracellular Ca2+ level in SH-SY5Y cells [P 923-929]
Yi-ching Chen, Tzyy-rong Jinn, Tse-yu ChUnG, Feng-yin Li, Ruey-jane FaN, Jason TC Tzen
[ Abstract ][ Full text ]


Cardiovascular Pharmacology

Differential regulations of blood pressure and perturbed metabolism by total ginseno­sides and conventional antihypertensive agents in spontaneously hypertensive rats [P 930-937]
Ji-ye AA, Guang-ji WANG, Hai-ping HAO, Qing HUANG, Yi-hong LU, Bei YAN, Wei-bin ZHA, Lin-sheng LIU, An KANG
[ Abstract ][ Full text ]


Gastrointestinal Pharmacology

The features of reserpine-induced gastric mucosal lesions [P 938-943]
Xiu-juan MA, Guo-cai LU, Shu-wei SONG, Wei LIU, Zhi-peng WEN, Xiang ZHENG, Qian-zhou LÜ,Ding-feng SU
[ Abstract ][ Full text ]


Gastrointestinal Pharmacology

Withagulatin A inhibits hepatic stellate cell viability and procollagen I production through Akt and Smad signaling pathways [P 944-952]
Qiong LIU, Jing CHEN, Xu WANG, Liang YU, Li-hong HU, Xu SHEN
[ Abstract ][ Full text ]


Endocrine Pharmacology

Geniposide inhibits high glucose-induced cell adhesion through the NF-κB signaling pathway in human umbilical vein endothelial cells [P 953-962]
Guang-fa WANG, Shao-yu WU, Wei XU, Hong JIN, Zheng-guang ZHU, Zhong-huang LI, Yuan-xin TIAN, Jia-jie ZHANG, Jin-jun RAO, Shu-guang WU
[ Abstract ][ Full text ]

AMPK enhances the expression of pancreatic duodenal homeobox-1 via PPARα, but not PPARγ, in rat insulinoma cell line INS-1 [P 963-969]
Hua GUO, Shui SUN, Xu ZHANG, Xiu-Juan ZHANG, Ling GAO, Jia-Jun ZHAO
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Antitumor Pharmacology

Inhibition of tumors cell growth in osteosarcoma-bearing SD rats through a combination of conventional and metronomic scheduling of neoadjuvant chemotherapy [P 970-976]
Xiao-zhong ZHU, Hong-mei YIN, Jiong MEI
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Molecular and cellular Pharmacology

Polymorphisms in the HOXD4 gene are not associated with peak bone mineral density in Chinese nuclear families [P 977-983]
Hao ZHANG, Jin-wei HE,  Gao Gao, Hua Yue , Jin-bo Yu,  Wei-wei Hu,  Jie-mei Gu, Yun-qiu Hu, Miao Li , Wen-zhen Fu, Yu-juan Liu, Zhen-lin Zhang
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A sensitive indirect competitive enzyme-linked immunosorbent assay for the detection of sarsasapogenin in rat plasma [P 984-989]
Jing WANG, Ji-hua LIU, Xu GUO, Jian ZHANG, Bo-yang YU
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Pharmaceutics

Novel vehicle based on cubosomes for ophthalmic delivery of flurbiprofen with low irritancy and high bioavailability [P 990-998]
Shun HAN, Jin-qiu SHEN, Yong GAN, Hai-ming GENG, Xin-xin ZHANG, Chun-liu ZHU, Li GAN
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Pharmacokinetics

Imatinib plasma trough concentration and its correlation with characteristics and response in Chinese CML patients [P 999-10048]
Qiu-bai LI, Chao CHEN, Zhi-chao CHEN, Hong-xiang WANG, Yan-lin WU, Yong YOU, Ping ZOU
[ Abstract ][ Full text ]


Drug Discovery

Discovery of novel PTP1B inhibitors with antihyperglycemic activity [P 1005-1012]
Zhang LIU, Qian CHAI, Yuan-yuan LI, Qiang SHEN, Lan-ping MA, Li-na ZHANG, Xin WANG, Li SHENG, Jing-ya LI, Jia LI, Jing-kang SHEN 
[ Abstract ][ Full text ]


APS Pharma-shelf for This Issue

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