Original Articles

Neuropharmacology

Baicalin attenuates oxygen-glucose deprivation-induced injury by inhibiting oxidative stress-mediated 5-lipoxygenase activation in PC12 cells [P 137-144]
Cheng-tan LI, Wei-ping ZHANG, San-hua FANG, Yun-bi LU, Li-hui ZHANG, Ling-ling QI, Xue-qin HUANG, Xiao-jia HUANG, Er-qing WEI
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Central administration of kisspeptin-10 inhibits natriuresis and diuresis induced by blood volume expansion in anesthetized male rats [P 145-149]
Xu HAN, Ming YAN, Xiao-fei AN, Ming HE, Jiang-yi YU
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Cardiovascular Pharmacology

Repurposing an old drug for a new use: glybenclamide exerts antiplatelet activity by interacting with the thromboxane A₂ receptor [P 150-159]
Harold J TING, Wallace J MURRAY, Fadi T KHASAWNEH
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Hydrogen peroxide stress stimulates phosphorylation of FoxO1 in rat aortic endothelial cells [P 160-164]
Ye-yu WANG, Si-min CHEN, Hao LI
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CPU86017, a berberine derivative, attenuates cardiac failure through normalizing calcium leakage and downregulated phospholamban and exerting antioxidant activity [P 165-174]
Min-you QI, Yu FENG, De-zai DAI, Na LI, Yu-si CHENG, Yin DAI
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Pulmonary Pharmacology

Protective role of PI3-kinase/Akt/eNOS signaling in mechanical stress through inhibition of p38 mitogen-activated protein kinase in mouse lung [P 175-183]
Xin-qi PENG, Mahendra DAMARLA, Jarrett SKIRBALL, Stephanie NONAS, Xiao-ying WANG, Eugenia J HAN, Emile J HASAN, Xuan CAO, Adel BOUEIZ, Rachel DAMICO, Rubin M TUDER, Alfred M SCIUTO, Dana R ANDERSON, Joe GN GARCIA, David A KASS, Paul M HASSOUN, Jun-tian ZHANG
[ Abstract ][ Full text ]

Endocrine Pharmacology

SLC22A2 gene 808 G/T variant is related to plasma lactate concentration in Chinese type 2 diabetics treated with metformin [P 184-190]
Qing LI, Fang LIU, Tai-shan ZHENG, Jun-ling TANG, Hui-juan LU, Wei-ping JIA
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Immunopharmacology

Immunomodulatory activity of andrographolide on macrophage activation and specific antibody response [P 191-201]
Wei WANG, Jing WANG, Sheng-fu DONG, Chun-hong LIU, Paola ITALIANI, Shu-hui SUN, Jing XU, Diana BORASCHI, Shi-ping MA, Di QU
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Anti-tumor Pharmacology

Downregulation of Dickkopf-1 is responsible for high proliferation of breast cancer cells via losing control of Wnt/β-catenin signaling  [P 202-210]
Xiao-lei ZHOU, Xiao-ran QIN, Xiao-dong ZHANG, Li-hong YE
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The epoxyeicosatrienoic acid-stimulated phosphorylation of EGF-R involves the activation of metalloproteinases and the release of HB-EGF in cancer cells  [P 211-218]
Li-ming CHENG, Jian-gang JIANG, Zi-yong SUN, Chen CHEN, Ryan T DACKOR, Darryl C ZELDIN, Dao-wen WANG
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Bicyclol protects HepG2 cells against D-galactosamine-induced apoptosis through inducing heat shock protein 27 and mitochondria associated pathway  [P 219-226]
Xiu-qi BAO, Geng-tao LIU
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Cellular and Molecular Pharmacology

Microarray analysis reveals the inhibition of nuclear factor-kappa B signaling by aristolochic acid in normal human kidney (HK-2) cells  [P 227-236]
Ya-yin CHEN, Su-yin CHIANG, Hsiu-ching WU, Shung-te KAO, Chien-yun HSIANG, Tin-yun HO, Jaung-geng LIN
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Pharmaceutics

Effect of lactoferrin- and transferrin-conjugated polymersomes in brain targeting: in vitro and in vivo evaluations [P 237-243]
Hui-le GAO, Zhi-qing PANG, Li FAN, Kai-li HU, Bing-xian WU, Xin-guo JIANG
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Drug Discovery

Structural studies of B-type Aurora kinase inhibitors using computational methods [P 244-258]
MM NEAZ, M MUDDASSAR, FA PASHA, Seung Joo CHO
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Cytotoxicity and reversal of multidrug resistance by tryptanthrin-derived indo­loquinazo­lines [P 259-264]
Sung-tsai YU, Ji-wang CHERN, Tzer-ming CHEN, Yi-fan CHIU, Hui-ting CHEN, Yen-hui CHEN
[ Abstract ][ Full text ]

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