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Review

MicroRNAs: a novel class of potential therapeutic targets for cardiovascular diseases [P 1-9]
Zhen-wei PAN, Yan-jie LU, Bao-feng YANG

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Original Articles

Cardiovascular Pharmacology  

Krüppel-like factor  (KLF) 5 mediates cyclin D1 expression and cell proliferation via   interaction with c-Jun in Ang II-induced VSMCs [P 10-18]
Yu LIU, Jin-kun WEN, Li-hua DONG, Bin ZHENG, Mei HAN

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Reduction in extracellular Ca2+ attenuates endothelium-dependent relaxation more than nitroprusside-induced relaxation [P 19-26]
Shigehiro HAYASHI, R Kelly HESTER

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Hepatic Pharmacology

Antifibrotic effects of ZK14, a novel nitric oxide-donating biphenyldicarboxylate derivative, on rat HSC-T6 cells and CCl4-induced hepatic fibrosis [P 27-34]
Li DAI, Hui JI, Xiang-wen KONG, Yi-hua ZHANG

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Endocrine and Renal Pharmacology

Atorvastatin improves insulin sensitivity in mice with obesity induced by monosodium glutamate [P 35-42]
Ning ZHANG, Yi HUAN, Hui HUANG, Guang-ming SONG, Su-juan SUN, Zhu-fang SHEN

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PPARγ agonists inhibit TGF-β-PKA signaling in glomerulosclerosis [P 43-50]
Rong ZOU, Gang XU, Xiao-cheng LIU, Min HAN, Jing-jing JIANG, Qian HUANG, Yong HE, Ying YAO

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Cellular and Molecular Pharmacology             

Effect of prototypical inducers on ligand activated nuclear receptor regulated drug disposition genes in rodent hepatic and intestinal cells [P 51-65]
Philip MARTIN, Robert RILEY, Paul THOMPSON, Dominic WILLIAMS, David BACK, Andrew OWEN

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Anti-tumor Pharmacology

Effect of betulinic acid on the regulation of Hiwi and cyclin B1 in human gastric adenocarcinoma AGS cells [P 66-72]
Li-jing YANG, Yan CHEN, Qi MA, Jun FANG, Jing HE, Yi-quan CHENG, Qiu-ling WU

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Aspirin inhibits proliferation of gemcitabine-resistant human pancreatic cancer cells and augments gemcitabine-induced cytotoxicity [P 73-80]
Yan-qiu OU, Wen-bo ZHU, Yan LI, Peng-xin QIU, Yi-jun HUANG, Jun XIE, Song-min HE, Xiao-ke ZHENG, Tian-dong LENG, Dong XU, Guang-mei YAN
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4’-Chloro-3,5-dihydroxystilbene, a resveratrol derivative, induces lung cancer cell death [P 81-92]
Jin-yi WU, Kun-wei TSAI, Jia-jen SHEE, Yi-zhen LI, Ching-hsein CHEN, Jing-jing CHUANG, Yi-wen LIU   
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Trichostatin A sensitizes cisplatin-resistant A549 cells to apoptosis by up-regulating death-associated protein kinase [P 93-101]
Jun WU, Cheng-ping HU, Qi-hua GU, Ye-peng LI, Min SONG    
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HIF-1α links β-adrenoceptor agonists and pancreatic cancer cells under normoxic condition [P 102-110]
Heng-tong HU, Qing-yong MA, Dong ZHANG, Su-gang SHEN, Liang HAN, Ya-dong MA, Ruo-fei LI, Ke-ping XIE    
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Application of RT-PCR in formalin-fixed and paraffin-embedded lung cancer tissues [P 111-117]
Fan ZHANG, Zhuo-min WANG, Hong-yu LIU, Yun BAI, Sen WEI, Ying LI, Min WANG, Jun CHEN, Qing-hua ZHOU  
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Pharmaceutics

Topical delivery of silymarin constituents via the skin route [P 118-126]
Chi-feng HUNG, Yin-ku LIN, Li-wen ZHANG, Ching-hsien CHANG, Jia-you FANG  
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Preparation, characterization and in vivo evaluation of bergenin-phospholipid complex [P 127-136]
Xuan QIN, Yang YANG, Ting-ting FAN, Tao GONG, Xiao-ning ZHANG, Yuan HUANG  
[ Abstract ][ Full text ]


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