Review

The neuroprotective mechanism of brain ischemic preconditioning [Page 1071-1080]
Liu XQ, Sheng R, Qin ZH
[ Abstract ][ Full text ]

Original Articles

Cardiovascular Pharmacology

Breviscapine ameliorates hypertrophy of cardio­myo­cytes induced by high glucose in diabetic rats via the PKC signaling pathway [Page 1081-1091]
Wang M, Zhang WB, Zhu JH, Fu GS, Zhou BQ
[ Abstract ][ Full text ]

Protective effects of betaglucin on myocardial tissue during myocardial infarction in rats and dogs [Page 1092-1098]
Qian J, Liu AJ, Zhang W, Wen ZP, Lin LL, Wang JH, Su DF, Liu JG
[ Abstract ][ Full text ]

Isoproterenol disperses distribution of NADPH oxidase, MMP-9, and pPKCε in the heart, which are mitigated by endothelin receptor antagonist CPU0213 [Page 1099-1106]
Cheng YS, Dai DZ, Dai Y
[ Abstract ][ Full text ]           

Glycine inhibits the LPS-induced increase in cyto­solic Ca²⁺ concentration and TNFα production in cardio­myocytes by activating a glycine receptor [Page 1107-1114]
Wang HD, Lü XX, Lu DX, Qi RB, Wang YP, Fu YM, Wang LW
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Beta-receptor activation increases sodium current in guinea pig heart [Page 1115-1122]
Wang HW, Yang ZF, Zhang Y, Yang JM, Liu YM, Li CZ
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Gastrointestinal, Renal, and Endocrine Pharmacology  

High K⁺-induced contraction requires depolariza­tion-induced Ca²⁺ release from internal stores in rat gut smooth muscle [Page 1123-1131]
Kirschstein T, Rehberg M, Bajorat R, Tokay T, Porath K, Köhling R  
[ Abstract ][ Full text ]

Effect of adrenotensin on cell proliferation is mediat­ed by angiotensin II in cultured rat mesangial cells [Page 1132-1137]
Xue H, Yuan P, Zhou L, Yao T, Huang Y, Lu LM    
[ Abstract ][ Full text ]

C/EBP beta and C/EBP delta expression is elevated in the early phase of ethanol-induced hepatosteatosis in mice [Page 1138-1143]
Chen YH, Yang CM, Chang SP, Hu ML  
[ Abstract ][ Full text ]

Immunopharmacology  

Periplocoside A prevents experimental auto­immune encephalomyelitis by suppressing IL-17 production and inhibits differentiation of Th17 cells [Page 1144-1152]
Zhang J, Ni J, Chen ZH,  Li X, Zhang RJ, Tang W, Zhao WM, Yang YF, Zuo JP  
[ Abstract ][ Full text ]

Anti-tumor Pharmacology  

Transformation of human liver L-O2 cells mediat­ed by stable HBx transfection [Page 1153-1161]
Zhang WY, Cai N, Ye LH, Zhang XD    
[ Abstract ][ Full text ]

Silibinin inhibits prostate cancer invasion, motility and migration by suppressing vimentin and MMP-2 expression [Page 1162-1168]
Wu KJ, Zeng J, Zhu GD, Zhang LL, Zhang D, Li L, Fan JH, Wang XY, He DL    
[ Abstract ][ Full text ]

Inhibition of MMP-3 activity and invasion of the MDA-MB-231 human invasive breast carcinoma cell line by bioflavonoids [Page 1169-1176]
Phromnoi K, Yodkeeree S, Anuchapreeda S, Limtrakul P   
[ Abstract ][ Full text ]

Molecular and Clinical Pharmacology

First step in pre-miRNAs processing by human Dicer [Page 1177-1185]
Flores-Jasso CF, Arenas-Huertero C, Reyes JL, Contreras-Cubas C, Covarrubias A, Vaca L
[ Abstract ][ Full text ]

Drug Discovery

Discovery of potent inhibitors for phospho­dies­terase 5 by virtual screening and pharma­cophore analysis [Page 1186-1194]
Chen CY, Chang YH, Bau DT, Huang HJ, Tsai FJ, Tsai CH, Chen CYC
[ Abstract ][ Full text ]

Novel 16-substituted bifunctional derivatives of huper­zine B: multifunctional cholinesterase inhi­bitors [Page 1195-1203]
Shi YF, Zhang HY, Wang W, Fu Y, Xia Y, Tang XC, Bai DL, He XC
[ Abstract ][ Full text ]

Molecular Genetics  

Early onset Paget’s disease of bone caused by a novel mutation (78dup27) of the TNFRSF 11A gene in a Chinese family [Page 1204-1210]
  Ke YH, Yue H, He JW, Liu YJ, Zhang ZL  
[ Abstract ][ Full text ]

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