Review

Cholinergic deficiency involved in vascular dementia: possible mechanism and strategy of treatment [Page 879-888]
Wang J, Zhang HY, Tang XC
[ Abstract ][ Full text ]

Original Articles

Neuropharmacology

Adenosine A₁ receptor-mediated transactivation of the EGF receptor produces a neuroprotective effect on cortical neurons in vitro [Page 889-898]
Xie KQ, Zhang LM, Cao Y , Zhu J, Feng LY
[ Abstract ][ Full text ]

Liquiritigenin inhibits Aβ_25-35-induced neurotoxicity and secretion of Aβ_1-40 in rat hippocampal neurons [Page 899-906]
Liu RT, Zou LB, Lü QJ
[ Abstract ][ Full text ]

Neuron differentiation and neuritogenesis stimulated by N-acetyl­cysteine (NAC) [Page 907-912]
Qian HR, Yang Y
[ Abstract ][ Full text ]

Silencing neuroglobin enhances neuronal vulnerability to oxidative injury by down-regulating 14-3-3 γ [Page 913-918]
Ye SQ, Zhou XY, Lai XJ, Zheng L, Chen XQ
[ Abstract ][ Full text ]

RNA interference-mediated downregulation of Beclin1 attenuates cerebral ischemic injury in rats [Page 919-927]
Zhang YQ, Liu JX, Li XZ, Xu L, Xu YG
[ Abstract ][ Full text ]

Cardiovascular Pharmacology  

Regulation of gap-junction protein connexin 43 by β-adrenergic receptor stimulation in rat cardiomyocytes [Page 928-934]
Xia Y, Gong KZ, Xu M, Zhang YY, Guo JH, Song Y, Zhang P 
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The peroxisome proliferator-activated receptor-α (PPAR-α) agonist, AVE8134, attenuates the progres­sion of heart failure and increases survival in rats [Page 935-946]
Linz W, Wohlfart P, Baader M, Breitschopf K, Falk E, Schafer HL, Gerl M, Kramer W, Rütten H  
[ Abstract ][ Full text ]

Chronic intermittent hypobaric hypoxia protects the heart against ischemia/reperfusion injury through upregulation of antioxidant enzymes in adult guinea pigs [Page 947-955]
Guo HC, Zhang Z, Zhang LN, Xiong C, Feng C, Liu Q, Liu X, Shi XL, Wang YL   
[ Abstract ][ Full text ]

The expression of efflux and uptake transporters are regulated by statins in Caco-2 and HepG2 cells [Page 956-964]
Rodrigues AC, Curi R, Genvigir FDV, Hirata MH, Hirata RDC  
[ Abstract ][ Full text ]

Pulmonary Pharmacology  

Alteration of airway responsiveness mediated by receptors in ovalbumin-induced asthmatic E3 rats [Page 965-972]
Long JW, Yang XD, Cao L , Lu SM, Cao YX    
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MS80, a novel sulfated oligosaccharide, inhibits pulmonary fibrosis by targeting TGF-β1 both in vitro and in vivo [Page 973-979]
Jiang HD, Guan HS    
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NAC is associated with additional alleviation of lung injury induced by invasive pulmonary aspergillosis in a neutropenic model [Page 980-986]
Xu P, Qu JM, Xu JF, Zhang J, Jiang HN, Zhang HJ    
[ Abstract ][ Full text ]

Gastrointestinal, Renal, and Endocrine Pharmacology  

Balsalazine decreases intestinal mucosal permeability of dextran sulfate sodium-induced colitis in mice [Page 987-993]
Liu XC, Mei Q, Xu JM, Hu J
[ Abstract ][ Full text ]

BMP6 reverses TGF-β1-induced changes in HK-2 cells: implica­tions for the treatment of renal fibrosis [Page 994-1000]
Yan JD, Yang S, Zhang J, Zhu TH
[ Abstract ][ Full text ]

Expression of Rho GDIα in rat osteoblasts intermittently exposed to parathyroid hormone in vitro and in vivo [Page 1001-1007]
Sun ZF, Jiang H, Ye ZQ, Jia B, Zhang XL, Zhang KQ
[ Abstract ][ Full text ]

Immunopharmacology  

Macrophage receptors of polysaccharide isolated from a marine filamentous fungus Phoma herbarum YS4108 [Page 1008-1014]
Chen S, Yin DK, Yao WB, Wang YD, Zhang YR, Gao XD  
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Efficacy of arbidol on lethal hantaan virus infections in suckling mice and in vitro [Page 1015-1024]
Deng HY, Luo F, Shi LQ, Zhong Q, Liu YJ, Yang ZQ
[ Abstract ][ Full text ]

Anti-tumor Pharmacology  

Lidamycin shows highly potent cytotoxic to myeloma cells and inhibits tumor growth in mice [Page 1025-1032]
Zhen YZ, Lin YJ, Li Y, Zhen YS  
[ Abstract ][ Full text ]

Marine-derived oligosaccharide sulfate (JG3) suppresses heparanase-driven cell adhesion events in heparanase over-expressing CHO-K1 cells [Page 1033-1038]
Li QN, Liu HY, Xin XL, Pan QM, Wang L, Zhang J, Chen Q, Geng MY, Ding J
[ Abstract ][ Full text ]

α 2,6-Hyposialylation of c-Met abolishes cell motility of ST 6Gal -I-knockdown HCT116 cells [Page 1039-1045]
Qian J, Zhu CH, Tang S, Shen AJ, Ai J, Li J, Geng MY, Ding J  
[ Abstract ][ Full text ]

Inhibition of autophagy induced by proteasome inhibition increases cell death in human SHG-44 glioma cells [Page 1046-1052]
Ge PF, Zhang JZ, Wang XF, Meng FK, Li WC, Luan YX, Ling F, Luo YN
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The antiproliferative effects of somatostatin receptor subtype 2 in breast cancer cells [Page 1053-1059]
He Y, Yuan XM, Lei P, Wu S, Xing W, Lan XL, Zhu HF, Huang T, Wang GB, An R, Zhang YX, Shen GX  
[ Abstract ][ Full text ]

Pharmacokinetics  

Pharmacokinetic studies of meloxicam following oral and transdermal administration in Beagle dogs [Page 1060-1064]
Yuan Y, Chen XY, Li SM, Wei XY, Yao HM, Zhong DF    
[ Abstract ][ Full text ]

Clinical Pharmacology  

Effects of hormone replacement therapy on magnetic resonance imaging of brain parenchyma hyperintensities in postmenopausal women [Page 1065-1070]
Liu YY, Hu L, Ji C, Chen DW, Shen X, Yang N, Yue Y, Jiang JM, Hong X, Ge QS, Zuo PP  
[ Abstract ][ Full text ]

Acknowledgements to Reviewers

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