Original Articles

Neuropharmacology

Involvement of the ipsilateral and contralateral cerebellum in the acquisition of unilateral classical eyeblink conditioning in guinea pigs [Page 141-152]
Hu B, Lin X, Huang LS, Yang L, Feng H, Sui JF
[ Abstract ][ Full text ]

Notch1 signaling inhibits growth of EC109 esophageal carcinoma cells through downmodulation of HPV18 E6/E7 gene expression [Page 153-158]
Zhang KJ, Lu QY, Niu XQ, Zhang P, Zhao JN, Wang Z, Hu JS, Li P, Liu WL
[ Abstract ][ Full text ]

Neuroprotection of geniposide against hydrogen peroxide induced PC12 cells injury: involvement of PI3 kinase signal pathway [Page 159-165]
Liu JH, Yin F, Guo LX, Deng XH, Hu YH
[ Abstract ][ Full text ]

Cardiovascular and Pulmonary Pharmacology

Inhibitory effects of tetrandrine on the Na⁺ channel of human atrial fibrillation myocardium [Page 166-174]
Chen L, Li QY, Yang Y, Li ZW, Zeng XR
[ Abstract ][ Full text ]

Proteomic analysis of the effect of iptakalim on human pulmonary arterial smooth muscle cell proliferation [Page 175-183]
Yang MX, Liu ZX, Zhang S, Jing Y, Zhang SJ, Xie WP, Ma L, Zhu CL, Wang H
[ Abstract ][ Full text ]

Oxidative modulation of marcaine and lekoptin in H9C2 rat myoblasts [Page 184-192]
Kulbacka J, Bar J, Chwilkowska A, Dumanska M, Drag-Zalesinska M, Wysocka T, Stach K, Bednarz I, Lugowski M, Marcinkowska A, Gamian A, Saczko J
[ Abstract ][ Full text ]

Sulfated tyrosines 27 and 29 in the N-terminus of human CXCR3 participate in binding native IP-10 [Page 193-201]
Gao JM, Xiang RL, Jiang L, Li WH, Feng QP, Guo ZJ, Sun Q, Zeng ZP, Fang FD
[ Abstract ][ Full text ]

Endocrine Pharmacology

Effect of geniposide, a hypoglycemic glucoside, on hepatic regulating enzymes in diabetic mice induced by a high-fat diet and streptozotocin [Page 202-208]
Wu SY, Wang GF, Liu ZQ, Rao JJ, Lü L, Xu W, Wu SG, Zhang JJ
[ Abstract ][ Full text ]


Immunopharmacology and Inflammation

Compound FLZ inhibits lipopolysaccharide-induced inflammatory effects via down-regulation of the TAK-IKK and TAK-JNK/p38MAPK pathways in RAW264.7 macrophages [Page 209-218]
Pang HY, Liu G, Liu GT
[ Abstract ][ Full text ]

Suppression of complete Freund’s adjuvant-induced adjuvant arthritis by cobratoxin [Page 219-227]
Liu YL, Lin HM, Zou R, Wu JC, Han R, Raymond LN, Reid PF, Qin ZH
[ Abstract ][ Full text ]

Heme oxygenase-1 mediates the anti-inflammatory effect of isoflurane preconditioning in LPS-stimulated macrophages [Page 228-234]
Li QF, Zhu YS, Jiang H, Xu H, Sun Y
[ Abstract ][ Full text ]

Anti-tumor Pharmacology

Different BAG-1 isoforms have distinct functions in modulating chemotherapeutic-induced apoptosis in breast cancer cells [Page 235-241]
Liu HY, Wang ZM, Bai Y, Wang M, Li Y, Wei S, Zhou QH, Chen J
[ Abstract ][ Full text ]

Clinical Pharmacology

The protective effect of the RAS inhibitor on diabetic patients with nephropathy in the context of VEGF suppression [Page 242-250]
Chen HB, Lu JX, Li Q, Bao YQ, Tang JL, Lu HJ, Xiang KS, Jia WP
[ Abstract ][ Full text ]

Drug Discovery

ScafBank: a public comprehensive Scaffold database to support molecular hopping [Page 251-258]
Yan BB, Xue MZ, Xiong B, Liu K, Hu DY, Shen JK
[ Abstract ][ Full text ]

Discovery of potent β-secretase (bace-1) inhibitors by the synthesis of isophthalamide-containing hybrids [Page 259-269]
Zhu YP, Xiao K, Yu HP, Ma LP, Xiong B, Zhang HY, Wang X, Li JY, Li J, Shen JK
[ Abstract ][ Full text]