Cover: Adenovirus-mediated expression of SSAT induces polyamine catabolism, decreases the cellular content of spermidine and spermine, and leads to the significant suppression of colorectal cancer cell growth, which provides a novel treatment option for colorectal cancer. (page 606-613).

  Vol 29 Issue 5 (2008)  

ORIGINAL ARTICLES

Neuropharmacology

5-HT_1A/7 receptor agonist excites cardiac vagal neurons via inhibition of both GABAergic and glycinergic inputs [Page 529-538]
Chen YH, Hou LL, Wang JJ
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Bilobalide inhibits 6-OHDA-induced activation of NF-κB and loss of dopaminergic neurons in rat substantia nigra [Page 539-547]
Li LY, Zhao XL, Fei XF, Gu ZL, Qin ZH, Liang ZQ
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Biological characters of [₁₈F]O-FEt-PIB in a rat model of Alzheimer's disease using micro-PET imaging [Page 548-554]
Zheng MQ, Yin DZ, Zhang L, Lei B, Cheng DF, Cai HC, Han YJ, Wu MX, Zhang H, Wang J
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Cardiovascular Pharmacology

Curcumin inhibits cellular cholesterol accumulation by regulating SREBP-1/caveolin-1 signaling pathway in vascular smooth muscle cells [Page 555-563]
Yuan HY, Kuang SY, Zheng X, Ling HY, Yang YB, Yan PK, Li K, Liao DF
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Functional subtypes of renal α₁-adrenoceptor in diabetic and non-diabetic 2K1C Goldblatt renovascular hypertension [Page 564-572]
Armenia A, Sattar MA, Abdullah NA, Khan MAH, Johns EJ
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Endocrine Pharmacology

Increased secretion and expression of amylin in spontaneously diabetic Goto-Kakizaki rats treated with rhGLP-1 (7-36) [Page 573-579]
Weng HB, Gu Q, Liu M, Cheng NN, Li D, Gao X
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Nitroglycerin enhances proliferation and osteoblastic differentiation in human mesenchymal stem cells via nitric oxide pathway [Page 580-586]
Huang L, Qiu N, Zhang C, Wei HY, Li YL, Zhou HH, Xiao ZS
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Downregulation of STEAP4, a highly-expressed TNF-α-inducible gene in adipose tissue, is associated with obesity in humans [Page 587-592]
Zhang CM, Chi X, Wang B, Zhang M, Ni YH, Chen RH, Li XN, Guo XR
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Chronic activation of neutral ceramidase protects β-cells against cytokine-induced apoptosis [Page 593-599]
Zhu Q, Jin JF, Shan XH, Liu CP, Mao XD, Xu KF, Liu C
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Urinary Pharmacology

Effect of long-term partial bladder outlet obstruction on caldesmon isoforms and their correlation with contractile function [Page 600-605]
Yang L, He DL, Wang S, Cheng HP, Wang XY
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Antitumor Pharmacology

Adenovirus-mediated expression of SSAT inhibits colorectal cancer cell growth in vitro [Page 606-613]
Sun H, Liu B, Yang YP, Xu CX, Yan YF, Wang W, Liu XX
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Synergy of gemcitabine and lidamycin associated with NF-κB downregulation in pancreatic carcinoma cells [Page 614-619]
Chen J, Wu SY, Ou-Yang ZG, Zhen YS
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Reversal effect of Ganoderma lucidum polysaccharide on multidrug resistance in K562/ADM cell line [Page 620-627]
Li WD, Zhang BD, Wei R, Liu JH, Lin ZB
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Berberine inhibits cyclin D1 expression via suppressed binding of AP-1 transcription factors to CCND1 AP-1 motif [Page 628-633]
Luo Y, Hao Y, Shi TP, Deng WW, Li N
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Drug screening

Identification of antiviral mimetic peptides with interferon α-2b-like activity from a random peptide library using a novel functional biopanning method [Page 634-640]
Zhang Q, Bai G, Chen JQ, Tian W, Cao Y, Pan PW, Wang C
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