Cover: Model of the mechanism of action of tumor suppressor RhoBTB. These proteins bind components of cullin3-dependent ubiquitin ligases and recruit substrates (in grey) for ubiquitinylation and subsequent degradation in the 26S proteasome. Alterations that impair the formation of the complex would contribute to tumor formation or progression (page 285-295).

  Vol 29 Issue 3 (2008)  

REVIEWS

Rho GTPases of the RhoBTB subfamily and tumorigenesis [Page 285-295]
Berthold J, Schenková K, Rivero F
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Arsenic trioxide: safety issues and their management [Page 296-304]
Au WY, Kwong YL
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ORIGINAL ARTICLES

Neuropharmacology

Agonist-induced hump current production in heterologously-expressed human α4β2-nicotinic acetylcholine receptors [Page 305-319]
Liu Q, Yu KW, Chang YC, Lukas RJ, Wu J
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Cellular and Molecular Pharmacology

Coexistence of qnrB4 and qnrS1 in a clinical strain of Klebsiella pneumoniae [Page 320-324]
Hu FP , Xu XG, Zhu DM, Wang MG
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Antitumor Pharmacology

Establishment and characteristics of two syngeneic human osteosarcoma cell lines from primary tumor and skip metastases [Page 325-332]
Zou CY, Wang J, Shen JN, Huang G, Jin S, Yin JQ, Guo QC, Li HM, Luo L, Zhang M, Zhang LJ
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NF-κB downregulation may be involved the depression of tumor cell proliferation mediated by human mesenchymal stem cells [Page 333-340]
Qiao L, Zhao TJ, Wang FZ, Shan CL, Ye LH, Zhang XD
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β-Sitosterol sensitizes MDA-MB-231 cells to TRAIL-induced apoptosis [Page 341-348]
Park C, Moon DO, Ryu CH, Choi BT, Lee WH, Kim GY, Choi YH
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Gambogic acid induces death inducer-obliterator 1-mediated apoptosis in Jurkat T cells [Page 349-354]
Wang Y, Chen Y, Chen Z, Wu Q, Ke WJ, Wu QL
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Roles of PI3-K/Akt pathways in nanoparticle realgar powders-induced apoptosis in U937 cells [Page 355-363]
Xi RG, Huang J, Li D, Wang XB, Wu LJ
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Association of nucleophosmin/B23 with bladder cancer recurrence based on immunohistochemical assessment in clinical samples [Page 364-370]
Tsui KH, Juang HH, Lee TH, Chang PL, Chen CL, Yung BYML
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Expression of PLK1 and survivin in non-Hodgkin's lymphoma treated with CHOP [Page 371-375]
Liu L, Zhang M, Zou P
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Pharmacokinetics

Identification of ginkgolide B metabolites in urine and rat liver cytochrome P450 enzymes responsible for their formation in vitro [Page 376-384]
Wang DL, Liang Y, Chen WD, Xie L, Wang GJ, Liu XD
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Drug Screening

Modeling resistance index of taxoids to MCF-7 cell lines using ANN together with electrotopological state descriptors [Page 385-396]
Dong PP, Zhang YY, Ge GB, Ai CZ, Liu Y, Yang L, Liu CX
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A novel high-throughput format assay for HIV-1 integrase strand transfer reaction using magnetic beads [Page 397-404]
He HQ, Ma XH, Liu B, Chen WZ, Wang CX, Cheng SH
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ACKNOWLEDGEMENTS TO REVIEWERS