Oringinal Articles

Neuropharmacology  

Synergistic effects of prostaglandin E1 and lithium in a rat model of cerebral ischemia [Page 1141-1149]
Han R, Gao B, Sheng R, Zhang LS, Zhang HL, Gu ZL, Qin ZH  
[ Abstract ][ Full text ]

Protective effects of TREK-1 against oxidative injury induced by SNP and H₂O₂ [Page 1150-1156]
Sun LN, Li LL, Li ZB, Wang L, Wang XL  
[ Abstract ][ Full text ]

Cardiovascular Pharmacology  

Effects of endogenous sulfur dioxide on monocrotaline-induced pulmonary hypertension in rats [Page 1157-1166]
Jin HF, Du SX, Zhao X, Wei HL, Wang YF, Liang YF, Tang CS, Du JB  
[ Abstract ][ Full text ]

Altered ATP-sensitive potassium channels may underscore obesity-triggered increase in blood pressure [Page1167-1174]
Fan LH, Tian HY, Ma AQ, Hu Z, Huo JH, Cao YX  
[ Abstract ][ Full text ]

Stimulation of Na⁺-Ca²⁺ exchange by purified antibody against alpha-2 repeat of Na⁺-Ca²⁺ exchanger in rat cardiomyocytes [Page 1175-1180]
Feng QL, Wu DM, Cui XL, Zhao HC, Fan GQ, Zhao LY, Wu BW  
[ Abstract ][ Full text ]

Tissue-specific effects of atorvastatin on 3-hydroxy-3-methylglutaryl-coenzyme A reductase expression and activity in spontaneously hypertensive rats [Page 1181-1186]
Chen GP, Yao L, Lu X, Li L, Hu SJ  
[ Abstract ][ Full text ]

Pulmonary Pharmacology  

Identification of higenamine in Radix Aconiti Lateralis Preparata as a beta2-adrenergic receptor agonist [Page 1187-1194]
Bai G, Yang Y, Shi Q, Liu Z, Zhang Q, Zhu YY
[ Abstract ][ Full text ]

Acetamide-45 inhibited hyperresponsiveness and airway inflammation in mice partly depending on phosphodiesterase activity suppression [Page 1195-1201]
Wang K, Shen HH, Huang HQ, Chen JC, Chen Z
[ Abstract ][ Full text ]

Aspergillus fumigatus conidia upregulates NOD2 protein expression both in vitro and in vivo [Page 1202-1208]
Zhang HJ, Qu JM, Shao CZ, Zhang J, He LX, Yuan ZH
[ Abstract ][ Full text ]

Endocrine Pharmacology  

Ginsenoside Rg1 promotes bone marrow stromal cells proliferation via the activation of the estrogen receptor-mediated signaling pathway [Page 1209-1214]
Lu XZ, Wang JH, Wu X, Zhou L, Wang L, Zhang XW, Cao KJ, Huang J
[ Abstract ][ Full text ]

Molecular Pharmacology  

Effects of RNAi-mediated inhibition of aggrecanase-1 and aggrecanase-2 on rat costochondral chondrocytes in vitro [Page 1215-1226]
Wang ZH, Yang ZQ, He XJ, Wang L, Li LX, Tu JB
[ Abstract ][ Full text ]

Discovery of sphingosine 1-O-methyltransferase in rat kidney and liver homogenates [Page 1227-1232]
Sacket SJ, Im DS
[ Abstract ][ Full text ]

Anti-cancer Pharmacology  

Apoptosis induced by diallyl disulfide in human breast cancer cell line MCF-7 [Page 1233-1239]
Lei XY, Yao SQ, Zu XY, Huang ZX, Liu LJ, Zhong M, Zhu BY, Tang SS, Liao DF
[ Abstract ][ Full text ]

Pharmacokinetics  

Discrimination analysis of mass spectrometry proteomics for ovarian cancer detection [Page 1240-1246]
Hong YJ, Wang XD, Shen D, Zeng S
[ Abstract ][ Full text ]

Effects of cyclosporin A and itraconazole on the pharmacokinetics of atorvastatin in rats [Page 1247-1252]
Dong J, Yu X, Wang L, Sun YB, Chen XJ, Wang GJ
[ Abstract ][ Full text ]

Pharmacokinetics/pharmacodynamics of antofloxacin hydrochloride in a neutropenic murine thigh model of Staphylococcus aureus infection [Page 1253-1260]
Xiao XM, Xiao YH
[ Abstract ][ Full text ]

Drug Screening  

Symmetrical 1-pyrrolidineacetamide showing anti-HIV activity through a new binding site on HIV-1 integrase [Page 1261-1267]
Du L, Zhao YX, Yang LM, Zheng YT, Tang Y, Shen X, Jiang HL
[ Abstract ][ Full text ]

Discovery and characterization of a novel inhibitor of CDC25B, LGH00045 [Page 1268-1274]
Feng X, Wang LN, Zhou YY, Yu HP, Shen Q, Zang Y, Zhou YB, Li JY, Zhang HX, Li J
[ Abstract ][ Full text ]