Cover: Purified NeuroD protein was internalized into intestinal cells both in vitro and in vivo efficiently. Nucleic localization of NeuroD in vivo was demonstrated by its co-localization with DAPI. According to its potential to restore euglycemia, this report suggested in vivo transduction of NeuroD protein into intestine might be a promising strategy for diabetes therapy (page 1181-1188).

  Vol 28 Issue 8 (2007)  

REVIEWS

From blood to brain: amoeboid microglial cell, a nascent macrophage and its functions in developing brain. [Page 1087-1096]
Kaur C, Dheen ST, Ling EA
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ORIGINAL ARTICLES

Neuropharmacology

Greater stress protein expression enhanced by combined prostaglandin A₁ and lithium in a rat model of focal ischemia. [Page 1097-1104]
Xu XH, Hua YN, Zhang HL, Wu JC, Miao YZ, Han R, Gu ZL, Qin ZH
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Morphine enhances purine nucleotide catabolism in vivo and in vitro. [Page 1105-1115]
Liu C, Liu JK, Kan MJ, Gao L, Fu HY, Zhou H, Hong M
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Tanshinone IIA inhibits endothelin-1 production in TNF-α-induced brain microvascular endothelial cells through suppression of endothelin-converting enzyme-1 synthesis. [Page 1116-1122]
Tang C, Wu AH, Xue HL, Wang YJ
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Propofol attenuates oxidative stress-induced PC12 cell injury via p38 MAP kinase dependent pathway. [Page 1123-1128]
Wu XJ, Zheng YJ, Cui YY, Zhu L, Lu Y, Chen HZ
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Effects of long-term, low-dose sex hormone replacement therapy on hippocampus and cognition of postmenopausal women of different apoE genotypes. [Page 1129-1135]
Yue Y, Hu L, Tian QJ, Jiang JM, Dong YL, Jin ZY, Cheng YH, Hong X, Ge QS, Zuo PP
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Cardiovascular Pharmacology

Serum sodium concentration is significantly associated with the angiographic characteristics of coronary atherosclerosis.[Page 1136-1142]
Jia EZ, Yang ZJ, Zhu TB, Wang LS, Chen B, Cao KJ, Huang J, Ma WZ
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Prevention of lipopolysaccharide-induced injury by 3,5-dicaffeoylquinic acid in endothelial cells.[Page 1143-1148]
Zha RP, Xu W, Wang WY, Dong L, Wang YP
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Inhibitory effect of ginsenoside Rb1 on calcineurin signal pathway in cardiomyocyte hypertrophy induced by prostaglandin F_2α.[Page 1149-1154]
Jiang QS, Huang XN, Yang GZ, Jiang XY, Zhou QX
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Electrophysiological effects of haloperidol on isolated rabbit Purkinje fibers and guinea pigs papillary muscles under normal and simulated ischemia.[Page 1155-1160]
Yan D, Cheng LF, Song HY, Turdi S, Kerram P
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Low-dose carvedilol reduces transmural heterogeneity of ventricular repolarization in congestive heart failure.[Page 1161-1165]
Zhong JH, Chen XP, Yun ML, Li WJ, Chen YF, Yao Z
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Pulmonary and Renal Pharmacology

Decreased expression of human aquaporin-5 correlated with mucus overproduction in airways of chronic obstructive pulmonary disease.[Page 1166-1174]
Wang K, Feng YL, Wen FQ, Chen XR, Ou XM, Xu D, Yang J, Deng ZP
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Propofol attenuation of renal ischemia/reperfusion injury involves heme oxygenase-1.[Page 1175-1180]
Wang HH, Zhou HY, Chen CC, Zhang XL, Cheng G
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Endocrine Pharmacology

Reversal of hyperglycemia by protein transduction of NeuroD in vivo.[Page 1181-1188]
Huang Y, Chen J, Li G, Cheng TY, Jiang MH, Zhang SY, Lu J, Yan S, Fan WW, Lu DR
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Role of hypothalamus nociceptin/orphanin FQ in pre-ovulatory luteinizing hormone surge of estrogen and progesterone-primed, ovariectomized rats.[Page 1189-1197]
An XF, Yu JY, Feng Y, Chen BY, Zhang SL
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11 beta-hydroxysteroid dehydrogenase type 1 promotes differentiation of 3T3-L1 preadipocyte.[Page 1198-1204]
Liu Y, Sun Y, Zhu T, Xie Y, Yu J, Sun WL, Ding GX, Hu G
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Antitumor Pharmacology

Molecular mechanisms of ZD1839 (Iressa)-induced apoptosis in human leukemic U937 cells.[Page 1205-1214]
Moon DO, Kim MO, Lee JD, Choi YH, Lee MK, Kim GY
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Antitumor effects of Chi-Shen extract from Salvia miltiorrhiza and Paeoniae radix on human hepatocellular carcinoma cells.[Page 1215-1223]
Hu S, Chen SM, Li XK, Qin R, Mei ZN
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Blockade of sonic hedgehog signal pathway enhances antipro-liferative effect of EGFR inhibitor in pancreatic cancer cells.[Page 1224-1230]
Hu WG, Liu T, Xiong JX, Wang CY
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Alendronate inhibits cell invasion and MMP-2 secretion in human chondrosarcoma cell line.[Page 1231-1235]
Lai TJ, Hsu SF, Li TM, Hsu HC, Lin JG, Hsu CJ, Chou MC, Lee MC, Yang SF, Fong YC
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Immunopharmacology

Enhanced efficacy of CTLA-4 fusion anti-caries DNA vaccines in gnotobiotic hamsters.[Page 1236-1242]
Zhang F, Li YH, Fan MW, Jia R, Xu QA, Guo JH, Yu F, Tian QW
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Pharmacokinetics

Influence of omeprazole on pharmacokinetics of domperidone given as free base and maleate salt in healthy Chinese patients.[Page 1243-1246]
Zhang YF, Chen XY, Dai XJ, Zhang YN, Liu QZ, Yu HL, Zhong DF
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Pharmacokinetics and tissue distribution of a novel PDE5 inhibitor, SK-3530, in rats.[Page 1247-1253]
Yoo HH, Kim NS, Im GJ, Kim DH
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Drug design

Design, synthesis and pharmacological evaluation of 4-[2-alkylthio-5(4)-(4-substitutedphenyl)imidazole-4(5)yl]benzenesulfonamides as selective COX-2 inhibitors.[Page 1254-1260]
Salimi M, Ghahremani MH, Naderi N, Amini M, Salimi E, Amanlou M, Abdi K, Salehi R, Shafiee A
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