Cover: Three-dimensional structural models of compound 1a in the active site of EGFR derived from the docking simulation (page 140-152).

  Vol 28 Issue 1 (2007)  

REVIEWS

Exploring in vitro roles of siRNA in cardiovascular disease. [Page 1-9]
Tang Y, Ge YZ, Yin JQ
[Extract][Full text]

ORIGINAL ARTICLES

Neuropharmacology

Endogenous histamine inhibits the development of morphine-induced conditioned place preference.[Page 10-18]
Gong YX, Lv M, Zhu YP, Zhu YY, Wei EQ, Shi H, Zeng QL, Chen Z
[Extract][Full text]

Neuroprotection of selenite against ischemic brain injury through negatively regulating early activation of ASK1/JNK cascade via activation of PI3K/AKT pathway.[Page 19-27]
Wang Q, Zhang QG, Wu DN, Yin XH, Zhang GY
[Extract][Full text]

Cardiovascular Pharmacology

Nitric oxide modulates hypoxic pulmonary smooth muscle cell proliferation and apoptosis by regulating carbon monoxide pathway.[Page 28-35]
Wang YF, Tian H, Tang CS, Jin HF, Du JB
[Extract][Full text]

Urotensin II accelerates cardiac fibrosis and hypertrophy of rats induced by isoproterenol.[Page 36-43]
Zhang YG, Li YG, Liu BG, Wei RH, Wang DM, Tan XR, Bu DF, Pang YZ, Tang CS
[Extract][Full text]

Hypoxia reoxygenation induces premature senescence in neonatal SD rat cardiomyocytes.[Page 44-51]
Zhang FX, Chen ML, Shan QJ, Zou JG, Chen C, Yang B, Xu DJ, Jin Y, Cao KJ
[Extract][Full text]

Cardioprotective effects of diltiazem reevaluated by a novel myocardial ischemic model in Chinese miniature swine.[Page 52-57]
Liu JX, Yu Z, Li XZ, Fu JH, Shang XH, Yan AG, Shi Y, Ma YL
[Extract][Full text]

Thrombolytic efficacy of native recombinant staphylo-kinase on femoral artery thrombus of rabbits.[Page 58-65]
Li CJ, Huang J, Yang ZJ, Cao KJ
[Extract][Full text]

Cellular and Molecular Pharmacology

CD151 gene delivery increases eNOS activity and induces ECV304 migration, proliferation and tube formation.[Page 66-72]
Zheng ZZ, Liu ZX
[Extract][Full text]

Serum amyloid A induces WISH cell apoptosis.[Page 73-80]
Jo SH, Yun J, Kim JM, Lee C, Baek SH, Bae YS
[Extract][Full text]

Gastrointestinal Pharmacology

Triptolide suppresses IL-1b-induced chemokine and stromelysin-1 gene expression in human colonic subepithelial myofibroblasts.[Page 81-88]
Tao QS, Ren JA, Li JS
[Extract][Full text]

Endocrine Pharmacology

Prevention of diabetic microangiopathy by prophylactic transplant of mobilized peripheral blood mononuclear cells.[Page 89-97]
Zhou B, Cao XC, Fang ZH, Zheng CL, Han ZB, Ren H, Poon MC, Han ZC
[Extract][Full text]

Immune tolerance induced by adoptive transfer of dendritic cells in an insulin-dependent diabetes mellitus murine model.[Page 98-104]
Zhang CL, Zou XL, Peng JB, Xiang M
[Extract][Full text]

Antitumor Pharmacology

Curcumin synergistically augments bcr/abl phosphoro-thioate antisense oligonucleotides to inhibit growth of chronic myelogenous leukemia cells.[Page 105-110]
Zhang KZ, Xu JH, Huang XW, Wu LX, Su Y, Chen YZ
[Extract][Full text]

Application of EGFP-EGF fusions to explore mechanism of endocytosis of epidermal growth factor.[Page 111-117]
Jiang H, Zhang J, Shi BZ, Xu YH, Li ZH, Gu JR
[Extract][Full text]

Pharmacokinetics

CYP3A4 mediated in vitro metabolism of vinflunine in human liver microsomes.[Page 118-124]
Zhao XP, Zhong J, Liu XQ, Wang GJ
[Extract][Full text]

Drug Screening

Development of a homogeneous calcium mobilization assay for high throughput screening of mas-related gene receptor agonists.[Page 125-131]
Zhang R, Yan PK, Zhou CH, Liao JY, Wang MW
[Extract][Full text]

Identification of human dopamine receptors agonists from Chinese herbs.[Page 132-139]
Zhang YL, Zhang HQ, Liu XY, Hua SN, Zhou LB, Yu J, Tan XH
[Extract][Full text]

Drug Design

Design, synthesis, antitumor evaluations and molecular modeling studies of novel 3,5-substituted indolin-2-one derivatives.[Page 140-152]
Li HH, Zhang XH, Tan JZ, Chen LL, Liu H, Luo XM, Shen X, Lin LP, Chen KX, Ding J, Jiang HL
[Extract][Full text]

INFORMATION FOR AUTHORS

ANNOUNCEMENTS35, 65