Cover: The change of radiosensitivity affected by hTR-specific antisense oligonucleotides and measured by comet assay. hTR-specific antisense oligonucleotides could increase radiation induced DNA damage and reduce the subsequent repair (page 1185-1191).

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ORIGINAL ARTICLES

Neuropharmacology

Caffeic acid ameliorates early and delayed brain injuries after focal cerebral ischemia in rats1[Page1103-1110]
Yu ZHOU, San-hua FANG, Yi-lu YE, Li-sheng CHU, Wei-ping ZHANG, Meng-ling WANG, Er-qing WEI2
[Extract][Full text]

Effects of (-)stepholidine in animal models for schizophrenia1 [Page1111-1118]
Bart A ELLENBROEK2,5, Xue-xiang ZHANG3,4, Guo-zhang JIN3
[Extract][Full text]

Microtubule stability and MAP1B upregulation control neuritogenesis in CAD cells[Page1119-1126]
Wen LI2,5, Jin-tang XIA3, Yue FENG4,5
[Extract][Full text]

Comparative studies of huperzine A, donepezil, and rivastigmine on brain acetylcholine, dopamine, norepinephrine, and 5-hydroxytryptamine levels in freely-moving rats1 [Page1127-1136]
Yan-qi LIANG, Xi-can TANG2
[Extract][Full text]

Comparison of antioxidant activities between salvianolic acid B and Ginkgo biloba extract (EGb 761)1[Page1137-1145]
Chang-suo LIU, Yong CHENG, Jin-feng HU, Wei ZHANG, Nai-hong CHEN, Jun-tian ZHANG2
[Extract][Full text]

 

Cardiovascular Pharmacology

PPARγ phosphorylation mediated by JNK MAPK: a potential role in macrophage-derived foam cell formation1[Page1146-1152]
Ran YIN2, Yu-gang DONG2,4, Hong-liang LI3
[Extract][Full text]

Differentiation of bone marrow mesenchymal stem cells induced by myocardial medium under hypoxic conditions[Page1153-1158]
Xiao-jie XIE1, Jian-an WANG1,3, Jiang CAO2, Xing ZHANG2
[Extract][Full text]

FAK-related nonkinase attenuates hypertrophy induced by angiotensin-II in cultured neonatal rat cardiac myocytes[Page1159-1164]
Jin QIN, Zheng-xiang LIU1
[Extract][Full text]

 

Antitumor Pharmacology

Cytotoxic and apoptotic effects of prenylflavonoid artonin B in human acute lymphoblastic leukemia cells1[Page1165-1174]
Chun-chung LEE2, Chun-nan LIN3, Guey-mei JOW4,5
[Extract][Full text]

Guanosine 5'-triphosphate induces differentiation-dependent apoptosis in human leukemia U937 and KG1 cells1[Page1175-1184]
Razieh YAZDANPARAST2, Mohammad Amin MOOSAVI, Majid MAHDAVI, Abbas LOTFI
[Extract][Full text]

Efficient inhibition of human telomerase activity by antisense oligonucleotides sensitizes cancer cells to radiotherapy [Page1185-1193]
Xue-mei JI2, Cong-hua XIE2, Ming-hao FANG3, Fu-xiang ZHOU2, Wen-jie ZHANG4, Ming-sheng ZHANG2, Yun-feng ZHOU2,5
[Extract][Full text]

 

Immunopharmacology

Protective effects of curcumin on methylglyoxal-induced oxidative DNA damage and cell injury in human mononuclear cells [Page1192-1198]
Wen-hsiung CHAN1, Hsin-jung WU
[Extract][Full text]

Neutral sulfate berberine modulates cytokine secretion and increases survival in endotoxemic mice1 [Page1199-1205]
Fei LI, Hua-dong WANG2, Da-xiang LU, Yan-ping WANG, Ren-bin QI, Yong-mei FU, Chu-jie LI
[Extract][Full text]

 

Pulmonary and Renal Pharmacology

Effective use of corticosteroids in treatment of plastic bronchitis with hemoptysis in Chinese adults[Page1206-1212]
Gang WANG1, You-juan WANG2, Feng-ming LUO2, Lei WANG1, Li-li JIANG3, Lin WANG4, Bing MAO1,5
[Extract][Full text]

CPU0213, a novel endothelin receptor antagonist, ameliorates septic renal lesion by suppressing ET system and NF-kB in rats  [Page1213-1221]
Hai-bo HE, De-zai DAI2, Yin DAI
[Extract][Full text]

Ginkgo biloba extract suppresses hypertrophy and extracellular matrix accumulation in rat mesangial cells1 [Page1222-1230]
Jian-yun WANG2, Xiao-xing YIN2,6, Yun-ming WU2, Dao-quan TANG2, Yuan-yuan GAO2, Mei-rong WAN4, Xiao-yu HOU3, Bei ZHANG5
[Extract][Full text]

 

Cellular and Molecular Pharmacology

A20 overexpression under control of mouse osteocalcin promoter in MC3T3-E1 cells inhibited tumor necrosis factor-alpha-induced apoptosis1 [Page1231-1237]
Yue-juan QIN2, Zhen-lin ZHANG2,4, Lu-yang YU3, Jin-wei HE2, Ya-nan HOU3, Tian-jin LIU3, Jia-cai WU3, Song-hua WU2, Li-he GUO3
[Extract][Full text]

Disulfide bond reduction corresponds to dimerization and hydrophobi-city changes of Clostridium botulinum type A neurotoxin[Page1238-1246]
Jiunn-jye WEY1, Shiao-shek TANG1, Tzong-yuan WU2,3
[Extract][Full text]

Conformational re-analysis of (+)-meptazinol: an opioid with mixed analgesic pharmacophores1[Page1247-1252]
Wei LI2, Xing-hai WANG2, Choi-wan LAU3, Yun TANG2,4, Qiong XIE2, Zhui-bai QIU2,5
[Extract][Full text]

 

Pharmacokinetics

Metabolism and metabolic inhibition of gambogic acid in rat liver microsomes1[Page1253-1258]
Yi-tong LIU, Kun HAO, Xiao-quan LIU 2, Guang-ji WANG
[Extract][Full text]

 

Drug Design

Design, synthesis and antitumor evaluation of a new series of N-substituted-thiourea derivatives[Page1259-1272]
Jian LI2, Jin-zhi TAN2, Li-li CHEN2, Jian ZHANG2, Xu SHEN2,3, Chang-lin MEI4,6, Li-li FU4, Li-ping LIN5, Jian DING5, Bing XIONG2, Xi-shan XIONG4, Hong LIU2,6, Xiao-min LUO2,6, Hua-liang JIANG2,3
[Extract][Full text]

 


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