Cover: Simplicity and complexity of calcium signaling. Ca2+ signals controlled by a relatively limited number of molecules exert their action within broad temporal and spatial domains (page 767-772).

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EDITORIAL

calcium signaling in physiology and pathophysiology  [Page767-772]
He-ping Cheng1,4, Sheng WEI1, Li-ping WEI2, Alexei Verkhratsky3,4
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REVIEWS

Glial calcium signaling in physiology and pathophysiology [Page773-780]
Alexei Verkhratsky2
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Ca2+ signaling during vertebrate somitogenesis  [Page781-790]
Sarah E WEBB, Andrew L MILLER2
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Ca2+ sparks as a plastic signal for skeletal muscle health, aging, and dystrophy [Page791-798]
Noah Weisleder, Jian-jie Ma1
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Molecular basis of inherited calcium channelopathies: role of mutations in pore-forming subunits  [Page799-812]
Lynn MCKEOWN, Philip ROBINSON, Owen T JONES2
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Store-operated calcium channels and pro-inflammatory signals [Page813-820]
Wei-chiao CHANG1
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Cross-talk between calcium and reactive oxygen species signaling [Page821-826]
Yuan YAN, Chao-liang WEI, Wan-rui ZHANG, He-ping CHENG, Jie LIU1
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Multiple mechanisms involved in oxytocin-induced modulation of myometrial contractility  [Page827-832]
Anatoly SHMYGOL1, Joanna GULLAM, Andrew BLANKS, Steven THORNTON
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Regulation of TRP-like muscarinic cation current in gastrointestinal smooth muscle with special reference to PLC/InsP3/Ca2+ system [Page833-842]
Alexander V ZHOLOS1
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Cytosolic calcium oscillations in submandibular gland cells [Page843-847]
Li SU, Chun-yan MA, Yan-dong ZHOU, Yan-hong JIA, Zong-jie CUI2
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ORIGINAL ARTICLES

Ca2+ sparks and Ca2+ glows in superior cervical ganglion neurons  [Page848-852]
Li-jun YAO2,3,4, Gang WANG3,4,, Kun-fu OU-YANG3, Chao-liang WEI3, Xian-hua WANG3, Shi-rong WANG3, Wei YAO3, Hong-ping HUANG3, Jian-hong LUO2, Cai-hong WU3, Jie LIU3, Zhuan ZHOU3,5, He-ping CHENG3,5
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S-Nitrosoglutathione and glutathione act as NMDA receptor agonists in cultured hippocampal neurons [Page853-860]
Ting-yu CHIN2, Sheau-huei CHUEH3,5, Pao-luh TAO4
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Cellular mechanism for spontaneous calcium oscillations in astrocytes  [Page861-868]
Tong-fei WANG2, Chen ZHOU2, Ai-hui TANG, Shi-qiang WANG, Zhen CHAI3
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MEK inhibitor PD98059 acutely inhibits synchronized spontaneous Ca2+ oscillations in cultured hippocampal networks [Page869-876]
Yan-fang RUI1, Zhao-hui SUN2, Jia-ping GU1, Zhong-hua SHENG1, Xiang-ping HE1, Zuo-ping XIE1,3
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Effect of osmotic stress on spontaneous calcium sparks in rat ventricular myocytes [Page877-887]
Hong XIE, Pei-hong ZHU1
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Molecular nature of sulfhydryl modification by hydrogen peroxide on type 1 ryanodine receptor  [Page888-894]
Hong-mei HAN2, Ri-sheng WEI2, Anthony F LAI3, Chang-cheng YIN2,4
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Role of inositol 1,4,5-trisphosphate receptors in a1-adrenergic receptor-induced cardiomyocyte hypertrophy [Page895-900]
Da-li LUO2,3,5, Jian GAO2, Xiao-mei LAN3, Gang WANG4, Sheng WEI4, Rui-ping XIAO4, Qi-de HAN3
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Developmental regulation of intracellular calcium transients during cardiomyocyte differentiation of mouse embryonic stem cells  [Page901-910]
Ji-dong Fu, Hui-mei Yu, Rong Wang, Ji Liang, Huang-tian Yang2
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Attenuation of mitochondrial, but not cytosolic, Ca2+ overload reduces myocardial injury induced by ischemia and reperfusion  [Page911-918]
Chun-mei CAO2,3,6, Wing-yee YAN3,6, Jing LIU3, Kenneth WL KAM3, Shi-zhong ZHAN4, James SK SHAM5, Tak-ming WONG3,7
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Insulin improves cardiomyocyte contractile function through enhancement of SERCA2a activity in simulated ischemia/reperfusion  [Page919-926]
Jie YU2, Hai-feng ZHANG2, Feng WU2, Qiu-xia LI2, Heng MA2, Wen-yi GUO3, Hai-chang WANG3, Feng GAO2,3,4,5
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Isoprenaline enhances local Ca2+ release in cardiac myocytes  [Page927-932]
Jian-xin SHEN2,3,4
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Characteristics of Ca2+-exocytosis coupling in isolated mouse pancreatic b cells [Page933-938]
Qian GE2,4, Yong-ming DONG2,4, Zhi-tao HU2, Zheng-xing WU2,5, Tao XU2,3,5
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Localized Ca2+ uncaging induces Ca2+ release through IP3R in smooth muscle  [Page939-944]
Min WANG, Zheng CHEN, Yan XING, Xu ZHANG, Xian-zhi DONG, Guang-ju JI1
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Residue Phe266 in S5-S6 loop is not critical for Charybdotoxin binding to Ca2+-activated K+ (mSlo1) channels  [Page945-949]
Jing YAO2, Hui LI2, Ge-liang GAN, Ying WU, Jiu-ping DING3
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Network regulation of calcium signal in stomatal development  [Page950-958]
Zhu-xia SHEN, Gen-xuan WANG2, Zhi-qiang LIU, Hao ZHANG, Mu-qing QIU, Xing-zheng ZHAO, Yi GAN
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