Cover: The expression of vascular endothelial growth factor (VEGF) in endothelial progenitor cell (EPC) treated with different concentrations of sonic hedgehog (shh) protein was analyzed by immunofluorescence. It showed that shh protein could promote VEGF expression in bone marrow-derived EPC and was promising in therapeutic angiogenesis (page 685-693).

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REVIEWS

Oncogenesis of RON receptor tyrosine kinase: a molecular target for malignant epithelial cancers [Page641-650]
Ming-hai WANG2,3,4, Hang-ping YAO2, Yong-qing ZHOU2
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ORIGINAL ARTICLES

Neuropharmacology

Protective effects of compound FLZ on b-amyloid peptide-(25-35)-induced mouse hippocampal injury and learning and memory impairment [Page651-658]
Fang FANG, Geng-tao LIU2
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Inhibition of ethanol-induced toxicity by tanshinone IIA in PC12 cells  [Page659-664]
Xian-fang MENG2, Xiao-jing ZOU3, Bin PENG2, Jing SHI2, Xin-min GUAN2, Chun ZHANG4,5

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Protective effects of iptakalim, a novel ATP-sensitive potassium channel opener, on global cerebral ischemia-evoked insult in gerbils  [Page665-672]
Hua CHEN2,4, Yong YANG2,4, Hong-hong YAO2, Xing-chun TANG2, Jian-hua DING2, Hai WANG3, Gang HU2,5
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High doses of bifendate elevate serum and hepatic triglyceride levels in rabbits and mice: animal models of acute hypertriglyceridemia1  [Page673-678]
Si-yuan PAN2,4, Rong YANG2, Yi-fan HAN3, Hang DONG2, Xu-dong FENG2, Na LI2, Wei GENG2, Kam-ming KO3

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Expression and purification of lipoprotein-associated phospholipase A2, a key enzyme involved in atherosclerosis [Page679-684]
Fu-jun ZHANG2,4, Mao-jun CAI3, Jing-kang SHEN3, Yi-ping WANG2,5
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Antitumor Pharmacology

Sonic hedgehog protein promotes bone marrow-derived endothelial progenitor cell proliferation, migration and VEGF production via PI 3-kinase/Akt signaling pathways  [Page685-693]
Jin-rong FU2, Wen-li LIU2,4, Jian-feng ZHOU2, Han-ying SUN2, Hui-zhen XU2, Li LUO2, Heng ZHANG2, Yu-feng ZHOU3
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Down-regulation of p210bcr/abl by curcumin involves disrupting molecular chaperone functions of Hsp90 [Page694-699]
Li-xian WU, Jian-hua XU2, Xiu-wang HUANG, Kun-zhong ZHANG, Cai-xia WEN, Yuan-zhong CHEN3
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Multiple actions of lysophosphatidylcholine in human Jurkat T cells  [Page700-707]
Young-jin IM2, Yun-kyung LEE2, Hae-young CHUNG3, Dong-soon IM2,4
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Pulmonary Pharmacology

Passive sensitization increases histamine-stimulated calcium signaling and NF-kB transcription activity in bronchial epithelial cells  [Page708-714]
Si JIN2,5, Dan TIAN3, Jian-guo CHEN4, Li-ping ZHU2, Sheng-yuan LIU2, Di-xun WANG2
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Hepatopharmacology

PPAR gamma inhibits growth of rat hepatic stellate cells and TGF beta-induced connective tissue growth factor expression [Page715-723]
Kai SUN, Qian WANG2, Xiao-hui HUANG
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Endocrine Pharmacology

Effect of nicotinamide on newly diagnosed type 1 diabetic children [Page724-727]
Madeeha Kamal1,2, Abdul-Jabbar Al Abbasy1, Ahood Al Muslemani1, Abdulbari Bener3,4,5

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Protective effect of steroidal saponins from rhizome of Anemarrhena asphodeloides on ovariectomy-induced bone loss in rats [Page728-734]
Hua NIAN2, Lu-ping QIN2, Wan-sheng CHEN3, Qiao-yan ZHANG2,4, Han-chen ZHENG2, Yin WANG 5

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Immunopharmacology

Anti-inflammatory effect of amurensin H on asthma-like reaction induced by allergen in sensitized mice [Page735-740]
Yi-tang LI2, Chun-suo YAO3, Jin-ye BAI2, Mao LIN3, Gui-fang CHENG2,4
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Recombinant human B7-H4 expressed in Escherichia coli inhibits T lymphocyte proliferation and IL-2 secretion in vitro [Page741-746]
Yi-xiang MAO2,3, Yong-Jing CHEN2, Yan GE2, Hong-bing MA2, Jian-feng YU2, Hong-ya WU2, Yu-min HU2, Qin WANG2, Qin SHI2, Xue-guang ZHANG2,4
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Pharmacokinetics

Pharmacokinetics and biodistribution of polymeric micelles of paclitaxel with Pluronic P123  [Page747-753]
Li-mei HAN, Jie GUO, Li-jun ZHANG, Qing-song WANG, Xiao-ling FANG2

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Pharmaceutics

In vitro characteristics of poly(lactic-co-glycolic acid) microspheres incorporating gelatin particles loading basic fibroblast growth factor  [Page754-759]
Shao-hong LI1,4, Shao-xi CAI1,3 , Bing LIU1, Kai-wang MA1, Zhen-ping WANG1, Xiao-kun LI2

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Drug Screening

High-throughput screening for monoamine oxidase-A and monoamine oxidase-B inhibitors using one-step fluorescence assay  [Page760-766]
Hong-mei GUANG, Guan-hua DU2
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