Cover: RNAi is a powerful tool to specifically knock down genes of interest. This exquisite sequence specificity
of RNAi provides a promising approach to address the complex interactions of viral and cellular regulatory proteins involved in different signal transduction pathways, such as NF-¦ÊB pathway (See pages 780¨C788).

previous issue  Vol 26 Issue 7 (2005)   next issue

REVIEWS

Plastins: versatile modulators of actin organization in (patho)physiological cellular processes.  [Page 769-779]
Delanote V, Vandekerckhove J, Gettemans J
[Extract] [Full text]

Dissecting role of regulatory factors in NF-kB pathway with siRNA.  [Page 780-788]
Guo J, Fu YC, Becerra CR
[Extract] [Full text]


ORIGINAL ARTICLES

Neuropharmacology

Activation of ERK/CREB pathway in spinal cord contributes to chronic constrictive injury-induced neuropathic pain in rats. [Page 789-798]
Song XS, Cao JL, Xu YB, He JH, Zhang LC, Zeng YM
[Extract] [Full text]

6-Hydroxydopamine-induced glutathione alteration occurs via glutathione enzyme system in primary cultured astrocytes. [Page 799-805]
Zhang J, Hu J, Ding JH, Yao HH, Hu G
[Extract] [Full text]

Cardiovascular Pharmacology
Phosphorylated heat shock protein 27 is involved in enhanced heart tolerance to ischemia in short-term type 1 diabetic rats. [Page 806-812]
Chen H, Wu XJ, LU XY, Zhu L, Wang LP, Yang HT, Chen HZ, Yuan WJ
[Extract] [Full text]

Isoflurane preconditioning protects against ischemia-reperfusion injury partly by attenuating cytochrome c release from subsarcolemmal mitochondria in isolated rat hearts. [Page 813-820]
Qian LP, Zhu SS, Cao JL, Zeng YM
[Extract] [Full text]

Taurine inhibits ischemia/reperfusion-induced compartment syndrome in rabbits. [Page 821-827]
Wang JX, Li Y, Zhang LK, Zhao J, Pang YZ, Tang CS, Zhang J
[Extract] [Full text]

Effect of hydrogen peroxide on persistent sodium current in guinea pig ventricular myocytes. [Page 828-834]
Ma JH, Luo AT, Zhang PH
[Extract] [Full text]

Expression of pro-inflammatory and anti-inflammatory cytokines in brain of atherosclerotic rats and effects of Ginkgo biloba extract. [Page 835-839]
Jiao YB, Rui YC, Li TJ, Yang PY, Qiu Y
[Extract] [Full text]

Genistein inhibits carotid sinus baroreceptor activity in anesthetized male rats. [Page 840-844]
Ma HJ, Liu YX, Wang FW, Wang LX, He RR, Wu YM
[Extract] [Full text]

Renal Pharmacology
Similar effects on rat renal mesangial cells by expressing different fragments of adrenomedullin gene in vitro. [Page 845-850]
Chen SW, Wang XF, Shao Y, Xue H, Zhou L, Yao T, Lu LM
[Extract] [Full text]

Ischemic preconditioning protects post-ischemic renal function in anesthetized dogs: role of adenosine and adenine nucleotides. [Page 851-859]
Li FZ, Kimura S, Nishiyama A, Rahman M, Zhang GX, Abe Y
[Extract] [Full text]

Endocrine Pharmacology
nteraction effects between estrogen receptor a and vitamin D receptor genes on age at menarche in Chinese women. [Page 860-864]
Xu H, Long JR, Li MX, Deng HW
[Extract] [Full text]

Inflammation Pharmacology
Design, synthesis, and anti-inflammatory evaluation of a series of novel amino acid-binding 1,5-diarylpyrazole derivatives. [Page 865-872]
Li MH, Yin LL, Cai MJ, Zhang WY, Huang Y, Wang X, Zhu XZ, Shen JK
[Extract] [Full text]

Anti-cancer Pharmacology
Regulating expressions of cyclin D1, pRb, and anti-cancer effects of deguelin on human Burkitt's lymphoma Daudi cells in vitro. [Page 873-880]
Liu HL, Chen Y, Cui GH, Wu QL, He J
[Extract] [Full text]

GLB prevents tumor metastasis of Lewis lung carcinoma by inhibiting tumor adhesion actions.[Page 881-886]
Pan Y, Song QL, Lin YH, Lu N, Yu HM, Li XJ
[Extract] [Full text]

Ocular Pharmacology
Tetramethylpyrazine protected photoreceptor cells of rats by modulating nuclear translocation of NF-kB. [Page 887-892]
Yang JN, Chen JM, Luo L, Lin SC, Li D, Hu SX
[Extract] [Full text]

Pharmacokinetics
Phase II metabolites of etofesalamide in filamentous fungi. [Page 893-896]
Huang HH, Ma GL, Sun YM, Li Q, Zhong DF
[Extract] [Full text]

 


Copyright©APS 2006
Add: 294 Tai-Yuan Road,Shanghai 200031,China
Phn: 86-21-5492-2821 Fax: 86-21-5492-2823
E-mail: aps@mail.shcnc.ac.cn