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Cover: A number of recombinant approaches are being exploited to the production of IgG-like bispecific antibodies. Compared to the smaller antibody fragments, the IgG-like bispecific antibodies contain the full-length Fc region which confers not only longer in vivo half-life, but also the capability of mediating immune effector mechanisms including antibody-dependent cellular cytotoxicity (see page 649-58). |
 Vol
26 Issue 6 (2005) 
REVIEWS
Antibody engineering: facing new challenges in cancer therapy.
[Page
641-648]
Sanz L, Cuesta ÁM, Compte M, Álvarez-Vallina L
[Extract]
[Full
text]
Recombinant approaches to IgG-like bispecific antibodies. [Page 649-658]
Marvin JS, Zhu ZP
[Extract] [Full text]
Cytogenetic and molecular genetic alterations in hepatocellular carcinoma. [Page 659-665]
Lau SH, Guan XY
[Extract] [Full text]
ORIGINAL
ARTICLES
Neuropharmacology
Gene expression profile of amyloid beta protein-injected mouse model for Alzheimer disease. [Page 666-672]
Kong LN, Zuo PP, Mu L, Liu YY, Yang N
[Extract]
[Full
text]
Effects of huperzine A on secretion of nerve growth factor in cultured rat cortical astrocytes and neurite outgrowth in rat PC12 cells.
[Page 673-678]
Tang LL, Wang R, Tang XC
[Extract]
[Full
text]
Overexpression of dishevelled-1 attenuates wortmannin-induced hyperphosphorylation of cytoskeletal proteins in N2a cell. [Page 679-684]
Wang HH, Zhang AH, Zhu LQ, Wang Q, Wang JZ
[Extract]
[Full
text]
Distribution of cysteinyl leukotriene receptor 2 in human traumatic brain injury and brain tumors. [Page
685-690]
Hu H, Chen G, Zhang JM, Zhang WP, Zhang L, Ge QF, Yao HT, Ding W, Chen Z, Wei EQ
[Extract]
[Full
text]
Cardiovascular
Pharmacology
Fibrin(ogen)olytic character of FIIa isolated from Agkistrodon acutus venom. [Page 691-695]
Wang YW, Liang XX, Chen JS, Chen Q, Qiu PX, Lin X, Yan GM
[Extract]
[Full
text]
Effects of simvastatin on cardiac performance and expression of sarcoplasmic reticular calcium regulatory proteins in rat heart. [Page 696-704]
Zheng X, Hu SJ
[Extract]
[Full
text]
Cell and Molecular Pharmacology
Differential regulation of cadherin expression by osteotropic
hormones and growth factors in vitro in human osteoprogenitor cells. [Page
705-713]
Liu P, Lin JH, Zhang B
[Extract]
[Full
text]
Pulmonary Pharmacology
Transforming growth factor-b1 gene polymorphisms associated
with chronic obstructive pulmonary disease in Chinese
population. [Page 714-720]
Su ZG, Wen FQ, Feng YL, Xiao M, Wu XL
[Extract]
[Full
text]
Endocrine Pharmacology
Protective effects of bendazac lysine on early experimental
diabetic nephropathy in rats. [Page 721-728]
Yin XX, Zhang YD, Shen JP, Wu HW, Zhu X, Li LM, Qiu J, Jiang SJ, Zheng XG
[Extract]
[Full
text]
Hepatopharmacology
Inhibitory effect of picroside II on hepatocyte apoptosis.
[Page 729-736]
Gao H, Zhou YW
[Extract]
[Full
text]
Altered expression of cytochrome P450 and possible correlation with preneoplastic changes in early stage of rat hepatocarcinogenesis. [Page 737-744]
Liu LL, Gong LK, Qi XM, Cai Y, Wang H, Wu XF, XiaoY, Ren J
[Extract]
[Full
text]
Melatonin-selenium nanoparticles protects liver against immunological injury induced by bacillus Calmette-Guérin and lipopolysaccharide. [Page 745-752]
Wang H, Wei W, Zhang SY, Shen YX, Wang NP, Yue L, Xu SY
[Extract] [Full text]
Antitumor Pharmacology
Peroxisome proliferator-activated receptor g ligands induce cell cycle arrest and apoptosis in human renal carcinoma cell lines. [Page 753-761]
Yang FG, Zhang ZW, Xin DQ, Shi CJ, Wu JP, Guo YL, Guan YF
[Extract]
[Full
text]
Inhibition of tumor growth and metastasis with antisense oligonucleotides (Cantide) targeting hTERT in an in situ human hepatocellular carcinoma model. [Page
762-768]
Lin RX, Tuo CW, Lü QJ, Zhang W, Wang SQ
[Extract]
[Full
text]
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