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Cover: Meptazinol is obviously devoid of noxious side effects such as respiratory depression and addiction, although both enantiomers were believed to be selective mu opiods agonists, an analgesic pharmacophore was established by extracting mean parameters from crystal structures of nine opiates. And enantiomers of meptazinol were superimposed respectively to this pharmacophore to find their similarity and difference ( page 334-348)
|
 Vol
26 Issue 3 (2005) 
EDITORIAL
A new season
of Chinese cardiovascular pharmacology research. [Page 257-258]
Chen AF,
Su DF
[Extract]
[Full
text]
REVIEW
Nitric oxide:
a newly discovered function on wound healing. [Page 259-264]
Luo JD,
Chen AF
[Extract]
[Full
text]
Functional
role of anion channels in cardiac diseases. [Page 265-278]
Duan DY,
Liu LLH, Bozeat N, Huang ZM, Xiang SY, Wang GL, Ye L, Hume
JR
[Extract]
[Full
text]
Small guanine
nucleotide-binding protein Rho and myocardial function.[Page 279-285]
Ren J, Fang CX
[Extract]
[Full
text]
The vanilloid
receptor and hypertension. [Page 286-294]
Wang
DH
[Extract]
[Full
text]
Historic
perspectives and recent advances in major animal models of hypertension.[Page
295-301]
Sun ZJ,
Zhang ZE
[Extract]
[Full
text]
Exo+
proofreading polymerases mediate genetic analysis and its application
in biomedical studies. [Page 302-306]
Liao DF,
Chen LL, Peng CY, Zhang J, Li K
[Extract]
[Full
text]
ORIGINAL
ARTICLES
Neuropharmacology
Gene expression profile induced by oral administration
of baicalin and gardenin after focal brain ischemia in rats. [Page 307-314]
Zhang ZJ, Wang Z, Zhang XY, Ying K, Liu JX,
Wang YY
[Extract]
[Full
text]
Cardiovascular
Pharmacology
Inducible nitric oxide synthase contributes to intermittent hypoxia
against ischemia/reperfusion injury. [Page 315-322]
Ding HL,
Zhu HF, Dong JW, Zhu WZ, Yang WW, Yang HT, Zhou ZN
[Extract]
[Full
text]
Regulation
of intracellular Ca2+ and calcineurin by NO/PKG in proliferation
of vascular smooth muscle cells. [Page 323-328]
Li SJ,
Sun NL
[Extract]
[Full
text]
Protective
effects of cariporide on endothelial dysfunction induced by high glucose.
[Page 329-333]
Wang
SX, Xiong XM, Song T, Liu LY
[Extract]
[Full
text]
Cellular
and Molecular Pharmacology
Structural comparisons of meptazinol with opioid analgesics. [Page
334-338]
Li W, Hao
JL, Tang Y, Chen Y, Qiu ZB
[Extract]
[Full
text]
Development
of a complex scintillation proximity assay for high-throughput screening
of PPARã modulators. [Page 339-344]
Wu B, Gao
J, Wang MW
[Extract]
[Full
text]
Endocrine
Pharmacology
Hypoglycemic effect of Astragalus polysaccharide and its
effect on PTP1B.
[Page 345-352]
Wu Y, Ou-Yang
JP, Wu K, Wang Y, Zhou YF, Wen CY
[Extract]
[Full
text]
Inflammation
Changes of 5-lipoxygenase pathway and proinflammatory mediators
in cerebral cortex and lung tissue of sensitized rats. [Page 353-358]
Deng YM,
Xie QM, Zhang SJ, Chen JQ, Yang QH, Bian RL
[Extract]
[Full
text]
Diethyldithiocarbamate
inhibits iNOS expression in human lens epithelial cells stimulated by
IFN-gamma and LPS. [Page 359-363]
Li DX,
Wang SL, Ito Y, Zhang JH, Wu CF
[Extract]
[Full
text]
Antitumor
Pharmacology
Antisense oligodeoxynucleotides targeting the serine/threonine kinase
Pim-2 inhibited proliferation of DU-145 cells. [Page 364-368]
Dai JM,
Zhang SQ, Zhang W, Lin RX, Ji ZZ, Wang SQ
[Extract]
[Full
text]
Effects of
spider Macrothele raven venom on cell proliferation and cytotoxicity
in HeLa cells. [Page 369-376]
Gao L,
Shan BE, Chen J, Liu JH, Song DX, Zhu BC
[Extract]
[Full
text]
Inhibition
of STAT3 expression by siRNA suppresses growth and induces apoptosis in
laryngeal cancer cells. [Page 377-383]
Gao LF,
Xu DQ, Wen LJ, Zhang XY, Shao YT, Zhao XJ
[Extract]
[Full
text]
Pharmacokinetics
Pharmacodynamic effects and kinetic disposition of rabeprazole in relation
to CYP2C19 genotype in healthy Chinese subjects. [Page 384-388]
Hu YM,
Xu JM, Mei Q, Xu XH, Xu SY
[Extract]
[Full
text]
Acknowledgement
to Reviewers
[PDF]
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